Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

ClinicalTrials.gov ID: NCT06915766

Public ClinicalTrials.gov record NCT06915766. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 6, 2026, 3:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Intermediate-Size Patient Population Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this expanded access program (EAP) protocol is to provide investigational bezuclastinib to patients with a diagnosis of nonadvanced systemic mastocytosis (NonAdvSM) or advanced systemic mastocytosis (AdvSM) who have received and failed or been intolerant to at least one standard approved therapy and/or have no comparable or satisfactory alternative therapy options.

Study identification

NCT ID: NCT06915766
Recruitment status: Available
Study type: Expanded access
Phase: Not listed
Lead sponsor: Cogent Biosciences, Inc.; Industry
Enrollment: Not listed

Conditions and interventions

Conditions

Interventions

Bezuclastinib Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Not listed
Primary completion: Not listed
Completion: Not listed
Last update posted: Jul 12, 2026

United States locations

U.S. sites: 23
U.S. states: 16
U.S. cities: 20

Facility	City	State	ZIP	Site status
Orso Health/Modena Asthma Allergy	La Jolla	California	92037	Available
Scripps Green Hospital	La Jolla	California	92037	Available
UCLA Ronald Reagan Medical Center	Los Angeles	California	90095	Available
Sneeze Wheeze & Itch Associates LLC Clinical Research Center	Normal	Illinois	61761	Available
Indiana University Health	Indianapolis	Indiana	46202	Available
Northern Light Eastern Maine Medical Center	Bangor	Maine	04401	Available
Walter Reed	Bethesda	Maryland	20889	Available
AllerVie Health	Glenn Dale	Maryland	20769	Available
Boston Specialists	Boston	Massachusetts	02111	Available
Dana Farber Cancer Institute	Boston	Massachusetts	02215	Available
Michigan Medicine- University of Michigan	Ann Arbor	Michigan	48109	Available
Mayo Clinic	Rochester	Minnesota	55905	Available
Washington University School of Medicine in St. Louis	St Louis	Missouri	63110	Available
Dartmouth-Hitchcock Medical Center	Lebanon	New Hampshire	03756	Available
Memorial Sloan Kettering Cancer Center	New York	New York	10065	Available
Duke Blood Cancer Center	Durham	North Carolina	27705	Available
The Ohio State University Wexner Medical Center	Columbus	Ohio	43210	Available
AIR Care	Dallas	Texas	75231	Available
Texas Children's Hospital	Houston	Texas	77030	Available
The University of Texas, MD Anderson Cancer Center	Houston	Texas	77030	Available
University of Utah - Huntsman Cancer Institute	Salt Lake City	Utah	84112	Available
Allergy Associates of Utah	Sandy City	Utah	84093	Available
Northwest Medical Specialties	Tacoma	Washington	98405	Available

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06915766, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jul 12, 2026 · Synced Sep 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06915766 live on ClinicalTrials.gov.

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