A Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASH
Public ClinicalTrials.gov record NCT06920043. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blinded, Placebo-controlled Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to Metabolic Dysfunction-associated Steatohepatitis (MASH)
Study identification
- NCT ID
- NCT06920043
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Boston Pharmaceuticals
- Industry
- Enrollment
- 42 participants
Conditions and interventions
Interventions
- Efimosfermin Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 8, 2025
- Primary completion
- Oct 31, 2027
- Completion
- Nov 30, 2027
- Last update posted
- Dec 23, 2025
2025 – 2027
United States locations
- U.S. sites
- 35
- U.S. states
- 12
- U.S. cities
- 30
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Liver Health - Chandler | Chandler | Arizona | 85224 | Recruiting |
| Arizona Liver Health - Peoria | Peoria | Arizona | 85381 | Recruiting |
| The Institute for Liver Health II LLC dba Arizona Liver Health - Tucson | Tucson | Arizona | 85712 | Recruiting |
| Fresno Clinical Research Center | Fresno | California | 93720 | Recruiting |
| OM Research LLC | Lancaster | California | 93534 | Recruiting |
| Knowledge Research Center | Orange | California | 92868 | Recruiting |
| California Liver Research Institute | Pasadena | California | 91105 | Recruiting |
| Inland Empire Liver Foundation | Rialto | California | 92377 | Recruiting |
| Santa Maria Gastroenterology Center | Santa Maria | California | 93458 | Recruiting |
| ClinCloud Research - Maitland | Maitland | Florida | 32751 | Withdrawn |
| ClinCloud Research - Viera | Melbourne | Florida | 32940 | Recruiting |
| Advanced Clinical Research of Miami | Miami | Florida | 33155 | Recruiting |
| Centricity Research - Columbus | Columbus | Georgia | 31904 | Recruiting |
| Gastrointestinal Specialists of Georgia PC | Marietta | Georgia | 30060 | Recruiting |
| Mercy Medical Center - Baltimore, Maryland | Baltimore | Maryland | 21202 | Recruiting |
| Gastrointestinal Associates and Endoscopy Center, PA - Flowood | Flowood | Mississippi | 39232 | Recruiting |
| Kansas City Research Institute | Kansas City | Missouri | 64131 | Recruiting |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | Recruiting |
| Coastal Research Institute, LLC | Fayetteville | North Carolina | 28304 | Recruiting |
| M3 Wake Research, Inc | Raleigh | North Carolina | 27612 | Recruiting |
| IMA Clinical Research - Austin, TX | Austin | Texas | 78745 | Recruiting |
| American Research Corporation - Austin, TX | Austin | Texas | 78757 | Recruiting |
| Pinnacle Clinical Research - Austin, TX | Austin | Texas | 78757 | Recruiting |
| The Liver Institute at Methodist Dallas Medical Center | Dallas | Texas | 75203 | Recruiting |
| Pinnacle Clinical Research - Georgetown | Georgetown | Texas | 78626 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Houston Research Institute - Texas Medical Center | Houston | Texas | 77030 | Recruiting |
| Houston Research Institute | Houston | Texas | 77079 | Recruiting |
| LinQ Research, LLC | Katy | Texas | 77494 | Recruiting |
| Houston Research Institute - Pasadena | Pasadena | Texas | 77505 | Recruiting |
| American Research Corporation - San Antonio | San Antonio | Texas | 78215 | Recruiting |
| Pinnacle Clinical Research - San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Velocity Clinical Research - Waco | Waco | Texas | 76710 | Recruiting |
| Richmond Institute for Veterans Research | Richmond | Virginia | 23249 | Recruiting |
| GI Alliance - Washington Gastroenterology | Tacoma | Washington | 98405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06920043, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Dec 23, 2025 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06920043 live on ClinicalTrials.gov.