A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)
Public ClinicalTrials.gov record NCT06924970. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Double-blind, Randomized, Placebo-Controlled, Multicenter, Dose- Finding, Efficacy, and Safety Study of Tebapivat in Participants With Sickle Cell Disease
Study identification
- NCT ID
- NCT06924970
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Agios Pharmaceuticals, Inc.
- Industry
- Enrollment
- 59 participants
Conditions and interventions
Conditions
Interventions
- Tebapivat Drug
- Tebapivat Matched Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 16 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2025
- Primary completion
- Apr 30, 2026
- Completion
- Apr 30, 2027
- Last update posted
- Apr 22, 2026
2025 – 2027
United States locations
- U.S. sites
- 17
- U.S. states
- 13
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCHealth at University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | — |
| UConn Health | Farmington | Connecticut | 06030-0001 | — |
| Children's National Hospital | Washington D.C. | District of Columbia | 20010 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Emory-Children's Center/ Children's Healthcare of Atlanta: Arthur M. Blank Hospital | Atlanta | Georgia | 30322 | — |
| Ann & Robert H. Lurie Children's Hospital of Chicago | Chicago | Illinois | 60611 | — |
| Boston Medical Center & Boston University School of Medicine | Boston | Massachusetts | 02118 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| Children's Hospital of Michigan | Detroit | Michigan | 48304 | — |
| Icahn School of Medicine at Mt. Sinai | New York | New York | 10029 | — |
| Montefiore Medical Center | The Bronx | New York | 10460 | — |
| Thomas Jefferson University Hospital | Philadelphia | Pennsylvania | 19107 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15232 | — |
| Lifespan at Rhode Island Hospital | Providence | Rhode Island | 02903-4923 | — |
| Prisma Health Cancer Institute - Farris Road | Greenville | South Carolina | 29605 | — |
| University of Texas Health Science Center of Houston | Houston | Texas | 77030 | — |
| Fred Hutchinson Cancer Center, University of Washington | Seattle | Washington | 98195 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06924970, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced Apr 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06924970 live on ClinicalTrials.gov.