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Active, not recruiting Phase 2 Interventional

A Dose-Finding Study of Tebapivat to Assess Efficacy, and Safety in Participants With Sickle Cell Disease (SCD)

ClinicalTrials.gov ID: NCT06924970

Public ClinicalTrials.gov record NCT06924970. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 8:01 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Double-blind, Randomized, Placebo-Controlled, Multicenter, Dose- Finding, Efficacy, and Safety Study of Tebapivat in Participants With Sickle Cell Disease

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study is to compare the effect of tebapivat versus placebo on anemia and to detect a dose-response for hemoglobin (Hb) response in participants with SCD.

Study identification

NCT ID
NCT06924970
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Agios Pharmaceuticals, Inc.
Industry
Enrollment
59 participants

Conditions and interventions

Eligibility (public fields only)

Age range
16 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
May 1, 2025 (Actual)
Primary completion
May 12, 2026 (Actual)
Completion
May 2027 (Estimated)
Last update posted
Sep 28, 2026

2025 – 2027

United States locations

U.S. sites
10
U.S. states
9
U.S. cities
9
Facility City State ZIP Site status
UConn Health Farmington Connecticut 06030-0001 —
MedStar Washington Hospital Center Washington D.C. District of Columbia 20010 —
Emory-Children's Center/ Children's Healthcare of Atlanta: Arthur M. Blank Hospital Atlanta Georgia 30322 —
Henry Ford Health System Detroit Michigan 48202 —
Children's Hospital of Michigan Detroit Michigan 48304 —
Icahn School of Medicine at Mt. Sinai New York New York 10029 —
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15232 —
Prisma Health Cancer Institute - Farris Road Greenville South Carolina 29605 —
University of Texas Health Science Center of Houston Houston Texas 77030 —
Fred Hutchinson Cancer Center, University of Washington Seattle Washington 98195 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 10 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06924970, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 28, 2026 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06924970 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →