ClinicalTrials.gov record
A Clinical Study of Ifinatamab Deruxtecan (I-DXd) in People With Metastatic Prostate Cancer (MK-2400-001)
ClinicalTrials.gov ID: NCT06925737
Public ClinicalTrials.gov record NCT06925737. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 9, 2026, 1:07 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Open-label Study of Ifinatamab Deruxtecan Versus Docetaxel in Participants With Metastatic Castration-Resistant Prostate Cancer (mCRPC) (IDeate-Prostate01)
Study identification
- NCT ID
- NCT06925737
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 1,440 participants
Conditions and interventions
Conditions
Interventions
- Docetaxel Drug
- Ifinatamab deruxtecan Drug
- Prednisone Drug
- Rescue Medication Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 12, 2025
- Primary completion
- Jun 25, 2028
- Completion
- Jan 5, 2031
- Last update posted
- May 7, 2026
2025 – 2031
United States locations
- U.S. sites
- 48
- U.S. states
- 26
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic in Arizona - Phoenix ( Site 0044) | Phoenix | Arizona | 85054 | Recruiting |
| City of Hope Comprehensive Cancer Center ( Site 0049) | Duarte | California | 91010 | Recruiting |
| City of Hope Lennar Foundation Cancer Center ( Site 0059) | Irvine | California | 92618 | Recruiting |
| Moores Cancer Center ( Site 0010) | La Jolla | California | 92093 | Recruiting |
| Cedars-Sinai Medical Center ( Site 0068) | Los Angeles | California | 90048 | Recruiting |
| UCLA Hematology/Oncology - Santa Monica ( Site 0002) | Los Angeles | California | 90404 | Recruiting |
| University of California, Irvine (UCI) Health - UC Irvine Medical Center ( Site 0006) | Orange | California | 92868 | Recruiting |
| Stanford Cancer Center ( Site 0046) | Palo Alto | California | 94304 | Recruiting |
| Rocky Mountain Regional Veterans Affairs Medical Center ( Site 0053) | Aurora | Colorado | 80045 | Recruiting |
| Yale-New Haven Hospital-Yale Cancer Center ( Site 0050) | New Haven | Connecticut | 06510 | Recruiting |
| Veterans Affairs Connecticut Healthcare System ( Site 0062) | West Haven | Connecticut | 06516 | Recruiting |
| The GW Medical Faculty Associates ( Site 0057) | Washington D.C. | District of Columbia | 20037 | Recruiting |
| Washington DC Veterans Affairs Medical Center ( Site 0056) | Washington D.C. | District of Columbia | 20422 | Recruiting |
| Mayo Clinic in Florida-Mayo Clinic Comprehensive Cancer Center ( Site 0077) | Jacksonville | Florida | 32224 | Recruiting |
| Emory University School of Medicine- Grady Campus ( Site 0103) | Atlanta | Georgia | 30303 | Recruiting |
| Winship Cancer Institute, Emory University ( Site 0003) | Atlanta | Georgia | 30322 | Recruiting |
| Rush University Medical Center-Hematology and Oncology ( Site 0028) | Chicago | Illinois | 60607 | Recruiting |
| University of Illinois at Chicago-University of Illinois Cancer Center ( Site 0063) | Chicago | Illinois | 60612 | Recruiting |
| University of Kentucky Chandler Medical Center ( Site 0048) | Lexington | Kentucky | 40536 | Recruiting |
| Greenebaum Comprehensive Cancer Center ( Site 0021) | Baltimore | Maryland | 21201 | Recruiting |
| Beth Israel Deaconess Medical Center ( Site 0043) | Boston | Massachusetts | 02215 | Recruiting |
| Dana Farber Cancer Institute ( Site 0012) | Boston | Massachusetts | 02215 | Recruiting |
| University of Michigan ( Site 0005) | Ann Arbor | Michigan | 48109 | Recruiting |
| Henry Ford Hospital ( Site 0035) | Detroit | Michigan | 48202 | Recruiting |
| Cancer and Hematology Centers of Western Michigan ( Site 0015) | Grand Rapids | Michigan | 49503 | Recruiting |
| Mayo Clinic in Rochester, Minnesota-Mayo Clinic Comprehensive Cancer Center ( Site 0078) | Rochester | Minnesota | 55905 | Recruiting |
| HealthPartners Cancer Research Center-HealthPartners Frauenshuh Cancer Center ( Site 0032) | Saint Louis Park | Minnesota | 55426 | Recruiting |
| HealthPartners Cancer Center at Regions Hospital ( Site 0052) | Saint Paul | Minnesota | 55101 | Recruiting |
| St. Vincent Frontier Cancer Center-Research ( Site 0037) | Billings | Montana | 59102 | Recruiting |
| Oncology Hematology West, PC dba Nebraska Cancer Specialists - Grand Island ( Site 0076) | Grand Island | Nebraska | 68803 | Completed |
| Oncology Hematology West P.C. dba Nebraska Cancer Specialists ( Site 0026) | Omaha | Nebraska | 68130 | Completed |
| John Theurer Cancer Center at Hackensack University Medical Center ( Site 0016) | Hackensack | New Jersey | 07601 | Recruiting |
| University of New Mexico Comprehensive Cancer Center ( Site 0022) | Albuquerque | New Mexico | 87131 | Recruiting |
| Icahn School of Medicine at Mount Sinai ( Site 0009) | New York | New York | 10029 | Recruiting |
| Great Lakes Cancer Care ( Site 0047) | Williamsville | New York | 14221 | Recruiting |
| The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C ( Site 0061) | Columbus | Ohio | 43221 | Recruiting |
| VA Portland Health Care System ( Site 0038) | Portland | Oregon | 97239 | Recruiting |
| Perelman Center for Advanced Medicine ( Site 0067) | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Abramson Cancer Center - Penn Medicine ( Site 0079) | Philadelphia | Pennsylvania | 19106 | Recruiting |
| Memphis VA Medical Center ( Site 0072) | Memphis | Tennessee | 38105 | Recruiting |
| SCRI Oncology Partners ( Site 0074) | Nashville | Tennessee | 37203 | Recruiting |
| UT Southwestern Medical Center ( Site 0039) | Dallas | Texas | 75390 | Recruiting |
| University of Texas-MD Anderson Cancer Center ( Site 0055) | Houston | Texas | 77030 | Recruiting |
| Blue Ridge Cancer Care ( Site 0024) | Roanoke | Virginia | 24014 | Recruiting |
| VA Puget Sound Health Care System ( Site 0054) | Seattle | Washington | 98108 | Recruiting |
| Fred Hutchinson Cancer Center ( Site 0060) | Seattle | Washington | 98109 | Recruiting |
| University Hospital and UW Health Clinics ( Site 0065) | Madison | Wisconsin | 53792 | Recruiting |
| Medical College of Wisconsin ( Site 0008) | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 234 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06925737, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06925737 live on ClinicalTrials.gov.