A Study to Investigate Progression-Free Survival With Sonrotoclax Plus Obinutuzumab Or Sonrotoclax Plus Rituximab Compared With Venetoclax Plus Rituximab Treatment In Patients With Relapsed and/or Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CELESTIAL-RRCLL)
Public ClinicalTrials.gov record NCT06943872. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Open-Label, Multicenter Study of Sonrotoclax Plus Anti-CD20 Antibody Therapies Versus Venetoclax Plus Rituximab in Patients With Relapsed/Refractory Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma
Study identification
- NCT ID
- NCT06943872
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- BeOne Medicines
- Industry
- Enrollment
- 630 participants
Conditions and interventions
Interventions
- Obinutuzumab Drug
- Rituximab Drug
- Sonrotoclax Drug
- Venetoclax Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 10, 2025
- Primary completion
- Sep 29, 2029
- Completion
- Nov 30, 2031
- Last update posted
- Apr 22, 2026
2025 – 2031
United States locations
- U.S. sites
- 33
- U.S. states
- 20
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Uci Health Laguna Hills | Laguna Hills | California | 92653 | Recruiting |
| Chao Family Comprehensive Cancer Center | Orange | California | 92868-3201 | Recruiting |
| Stanford Cancer Institute | Palo Alto | California | 94304-2205 | Recruiting |
| Scripps Prebys Cancer Center | San Diego | California | 92103-2106 | Recruiting |
| Rocky Mountain Cancer Centers (Williams) Usor | Aurora | Colorado | 80012-5405 | Recruiting |
| Yale University, Yale Cancer Center | New Haven | Connecticut | 06520-8028 | Recruiting |
| Eastern Connecticut Hematology and Oncology | Norwich | Connecticut | 06360-2700 | Recruiting |
| Cleveland Clinic Florida | Weston | Florida | 33331-3609 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Illinois Cancer Specialists (Niles) Usor | Niles | Illinois | 60714-5905 | Recruiting |
| University of Louisville, Brown Cancer Center | Louisville | Kentucky | 40202 | Recruiting |
| Mary Bird Perkins Cancer Center | Baton Rouge | Louisiana | 70809-3738 | Recruiting |
| University of Maryland Greenebaum Comprehensive Cancer Center | Baltimore | Maryland | 21201-1544 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02215-5418 | Recruiting |
| The Cancer and Hematology Centers | Grand Rapids | Michigan | 49503-2563 | Recruiting |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905-0001 | Recruiting |
| Sidney Kimmel Comprehensive Cancer Center Washington Twp | Sewell | New Jersey | 08080 | Recruiting |
| Memorial Sloan Kettering Cancer Center Mskcc | New York | New York | 10065-6800 | Recruiting |
| Clinical Research Alliance, Inc | Westbury | New York | 11590-5119 | Recruiting |
| University of North Carolina At Chapel Hill | Chapel Hill | North Carolina | 27514-4220 | Recruiting |
| Levine Cancer Center | Charlotte | North Carolina | 28204-2990 | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | Recruiting |
| Oncology Hematology Care Clinical Trials, Llc | Cincinnati | Ohio | 45245-1995 | Recruiting |
| Oncology Associates of Oregon Willamette Valley Cancer Center | Eugene | Oregon | 97401 | Recruiting |
| Penn State Milton S Hershey Medical Center | Hershey | Pennsylvania | 17033 | Recruiting |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107-4216 | Recruiting |
| Upmc Hillman Cancer Center(Univ of Pittsburgh) | Pittsburgh | Pennsylvania | 15232-1309 | Recruiting |
| Tennessee Oncology Greco Hainsworth Centers For Research Chattanooga | Chattanooga | Tennessee | 37404 | Recruiting |
| Tennessee Oncology | Nashville | Tennessee | 37205 | Recruiting |
| Texas Oncology Baylorcharles A Sammons Cancer Center | Dallas | Texas | 75246-2003 | Recruiting |
| Texas Oncology San Antonio Medical Center Usor | San Antonio | Texas | 78240-5251 | Recruiting |
| Texas Oncology Tyler | Tyler | Texas | 75702-7522 | Recruiting |
| Northwest Cancer Specialist, Pc(Us Oncology Research) | Vancouver | Washington | 98684-6930 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 134 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06943872, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 22, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06943872 live on ClinicalTrials.gov.