A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Public ClinicalTrials.gov record NCT06948422. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Master Protocol to Investigate the Efficacy and Safety of Orforglipron Once Daily in Participants With Hypertension and Obesity or Overweight: Randomized, Double-Blind, Placebo-Controlled Trials (ATTAIN-HYPERTENSION)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The GZPL master protocol will support 2 independent studies, J2A-MC-GZL1 (GZL1) and J2A-MC-GZL2 (GZL2). The purpose of this study is to create a framework to evaluate the safety and efficacy of orforglipron for the treatment of hypertension in participants with obesity or overweight.
Study identification
- NCT ID
- NCT06948422
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 974 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2025 (Actual)
- Primary completion
- Sep 2027 (Estimated)
- Completion
- Sep 2027 (Estimated)
- Last update posted
- May 29, 2026
2025 – 2027
United States locations
- U.S. sites
- 29
- U.S. states
- 18
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Elite Clinical Studies, LLC | Phoenix | Arizona | 85018 | — |
| Valley Clinical Trials, Inc. | Covina | California | 91723 | — |
| Valley Clinical Trials, Inc. | Northridge | California | 91325 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Excel Medical Clinical Trials | Boca Raton | Florida | 33434 | — |
| Care Access - Brandon | Brandon | Florida | 33510 | — |
| Northeast Research Institute - Downtown Office | Jacksonville | Florida | 32204 | — |
| Care Access - St. Petersburg | St. Petersburg | Florida | 33710 | — |
| East-West Medical Research Institute | Honolulu | Hawaii | 96814 | — |
| Sinai Hospital Of Baltimore | Baltimore | Maryland | 21209 | — |
| Ascension Saint Agnes Heart Care | Baltimore | Maryland | 21229 | — |
| Lucida Clinical Trials | New Bedford | Massachusetts | 02740 | — |
| Arcturus Healthcare , PLC, Troy Internal Medicine Research Division | Troy | Michigan | 48098 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Excel Clinical Research, LLC | Las Vegas | Nevada | 89109 | — |
| Palm Research Center Sunset | Las Vegas | Nevada | 89148 | — |
| Rochester Clinical Research, LLC | Rochester | New York | 14609 | — |
| Remington-Davis, Inc | Columbus | Ohio | 43215 | — |
| PriMED Clinical Research | Dayton | Ohio | 45429 | — |
| Advanced Research Institute - Tigard | Tigard | Oregon | 97223 | — |
| Care Access - Mauldin | Mauldin | South Carolina | 29662 | — |
| Dallas Heart and Vascular Consultants, PA | Duncanville | Texas | 75137 | — |
| Texas Institute of Cardiology, PA | McKinney | Texas | 75071 | — |
| North Hills Family Medicine/North Hills Medical Research | North Richland Hills | Texas | 76180 | — |
| Advanced Research Institute | Ogden | Utah | 84405 | — |
| Carient Heart & Vascular - Manassas | Manassas | Virginia | 20109 | — |
| Health Research of Hampton Roads, Inc. | Newport News | Virginia | 23606 | — |
| National Clinical Research, Inc | Richmond | Virginia | 23294 | — |
| Eastside Research Associates | Redmond | Washington | 98052 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 71 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06948422, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 29, 2026 · Synced Oct 31, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06948422 live on ClinicalTrials.gov.