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Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Gastrointestinal Stromal Tumors

ClinicalTrials.gov ID: NCT06948955

Public ClinicalTrials.gov record NCT06948955. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:35 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Expanded Access to Bezuclastinib to be Coadministered With Sunitinib for Patients With Locally Advanced, Unresectable, or Metastatic Gastrointestinal Stromal Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this expanded access program (EAP) is to provide investigational bezuclastinib so that it can be coadministered with sunitinib to patients with a diagnosis of gastrointestinal stromal tumors (GIST) with no comparable or satisfactory alternative therapy options. The combination of bezuclastinib and sunitinib provides broad inhibition of all primary and secondary KIT mutations that commonly occur in GIST.

Study identification

NCT ID
NCT06948955
Recruitment status
Available
Study type
Expanded access
Phase
Not listed
Lead sponsor
Cogent Biosciences, Inc.
Industry
Enrollment
Not listed

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Not listed

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Not listed
Primary completion
Not listed
Completion
Not listed
Last update posted
Jul 12, 2026

United States locations

U.S. sites
25
U.S. states
18
U.S. cities
23
Facility City State ZIP Site status
Mayo Clinic Hospital Phoenix Arizona 85054 Available
USC/Norris Comprehensive Cancer Center Los Angeles California 90033 Available
UCLA Department of Medicine- Hematology/Oncology Los Angeles California 90095 Available
University of Colorado Aurora Colorado 80045 Available
Smillow Cancer Hospital - Yale New Haven Health New Haven Connecticut 06510 Available
Mayo Clinic Jacksonville Florida 32224 Available
Orlando Health Orlando Florida 32806 Available
Northwestern Memorial Hospital Chicago Illinois 60611 Available
The University of Chicago Medical Center Chicago Illinois 60637 Available
Johns Hopkins University Baltimore Maryland 21287 Available
Dana Farber Cancer Institute (DFCI) Boston Massachusetts 02215 Available
Karmanos Cancer Institute Detroit Michigan 48201 Available
Mayo Clinic Rochester Minnesota 55905 Available
Roswell Park Cancer Institute Buffalo New York 14263 Available
Memorial Sloan Kettering Cancer Center New York New York 10065 Available
Cleveland Clinic Foundation Cleveland Ohio 44195 Available
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center Columbus Ohio 43210 Available
Taylor Cancer Research Center Maumee Ohio 43537 Available
Oregon Health and Sciences University Portland Oregon 97239 Available
Thomas Jefferson University Philadelphia Pennsylvania 19107 Available
UPMC Hillman Cancer Center Pittsburgh Pennsylvania 15232 Available
MD Anderson Cancer Center Houston Texas 77030 Available
Huntsman Cancer Institute, University of Utah Salt Lake City Utah 84112 Available
Shenandoah Oncology Winchester Virginia 22601 Available
Northwest Medical Specialties Tacoma Washington 98405 Available

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06948955, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 12, 2026 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06948955 live on ClinicalTrials.gov.

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