Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

ClinicalTrials.gov ID: NCT06950385

Public ClinicalTrials.gov record NCT06950385. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 7:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Multi-Site, Prospective, Randomized, Double-Blind, Placebo-Controlled Trial of eRapa to Improve Clinical Outcomes in Patients With Familial Adenomatous Polyposis

Study identification

NCT ID: NCT06950385
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Rapamycin Holdings Inc.; Industry
Enrollment: 168 participants

Conditions and interventions

Conditions

Familial Adenomatous Polyposis (FAP)

Interventions

Placebo Drug
eRapa (encapsulated rapamycin) Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 17, 2025
Primary completion: Jun 30, 2030
Completion: Dec 31, 2030
Last update posted: Mar 16, 2026

2025 – 2031

United States locations

U.S. sites: 18
U.S. states: 14
U.S. cities: 17

Facility	City	State	ZIP	Site status
City of Hope	Arcadia	California	91007	Not yet recruiting
Yale Cancer Center	New Haven	Connecticut	06520	Recruiting
Georgetown University	Washington D.C.	District of Columbia	20057	Recruiting
Digestive & Liver Center of Florida	Orlando	Florida	32825	Recruiting
Cleveland Clinic Florida	Weston	Florida	33331	Recruiting
University of Chicago	Chicago	Illinois	60615	Not yet recruiting
University of Kansas Medical Center	Kansas City	Kansas	66160	Recruiting
Johns Hopkins University	Baltimore	Maryland	21205	Recruiting
Dana Farber Cancer Institute	Boston	Massachusetts	02115	Not yet recruiting
University of Michigan	Ann Arbor	Michigan	48109	Recruiting
Department of Surgery, Section of Colon Rectal and Surgery	St Louis	Missouri	63110	Recruiting
Cleveland Clinic	Cleveland	Ohio	44195	Recruiting
Ohio State University	Columbus	Ohio	43210	Recruiting
Geisinger Medical Center	Danville	Pennsylvania	17822	Recruiting
University of Pittsburgh Medical Center	Pittsburgh	Pennsylvania	15213	Recruiting
The University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Benaroya Research Institute at Virginia Mason	Seattle	Washington	98101	Recruiting
University of Washington - Fred Hutchinson	Seattle	Washington	98195	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 8 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06950385, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Mar 16, 2026 · Synced May 20, 2026

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The complete protocol, eligibility criteria, and contact information for NCT06950385 live on ClinicalTrials.gov.

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