Study to Evaluate the Efficacy and Safety of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa (TRuE-HS2)
Public ClinicalTrials.gov record NCT06958211. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Double-Blind, Randomized, Vehicle-Controlled, Efficacy and Safety Study of Ruxolitinib Cream in Participants With Hidradenitis Suppurativa
Study identification
- NCT ID
- NCT06958211
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Incyte Corporation
- Industry
- Enrollment
- 550 participants
Conditions and interventions
Conditions
Interventions
- Ruxolitinib Cream Drug
- Vehicle Cream Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 11, 2025
- Primary completion
- Oct 8, 2026
- Completion
- Jul 10, 2027
- Last update posted
- Apr 7, 2026
2025 – 2027
United States locations
- U.S. sites
- 67
- U.S. states
- 28
- U.S. cities
- 60
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Investigative Site US257 | Birmingham | Alabama | 35203 | Recruiting |
| Investigative Site US218 | Birmingham | Alabama | 35244 | Recruiting |
| Investigative Site US239 | Montgomery | Alabama | 36117 | Recruiting |
| Investigative Site US215 | Phoenix | Arizona | 85006 | Recruiting |
| Investigative Site US261 | Phoenix | Arizona | 85037 | Recruiting |
| Investigative Site US240 | Tucson | Arizona | 85718 | Recruiting |
| Investigative Site US262 | Encino | California | 91436 | Recruiting |
| Investigative Site US222 | Fountain Valley | California | 92708 | Recruiting |
| Investigative Site US211 | Los Angeles | California | 90045 | Recruiting |
| Investigative Site US237 | Los Angeles | California | 90056 | Recruiting |
| Investigative Site US234 | Northridge | California | 91325 | Recruiting |
| Investigative Site US250 | Santa Ana | California | 92706 | Recruiting |
| Investigative Site US244 | Castle Rock | Colorado | 80109 | Recruiting |
| Investigative Site US252 | Cromwell | Connecticut | 06416 | Recruiting |
| Investigative Site US208 | Boca Raton | Florida | 33486 | Recruiting |
| Investigative Site US203 | Hialeah | Florida | 33012-3618 | Recruiting |
| Investigative Site US258 | Jacksonville | Florida | 32216 | Recruiting |
| Investigative Site US206 | Maitland | Florida | 32751 | Recruiting |
| Investigative Site US223 | Miami | Florida | 33136 | Recruiting |
| Investigative Site US241 | Miami | Florida | 33147 | Recruiting |
| Investigative Site US202 | Miami | Florida | 33173 | Recruiting |
| Investigative Site US214 | Tampa | Florida | 33609 | Recruiting |
| Investigative Site US247 | Tampa | Florida | 33612 | Recruiting |
| Investigative Site US231 | Columbus | Georgia | 31904 | Recruiting |
| Investigative Site US225 | Sandy Springs | Georgia | 30328 | Recruiting |
| Investigative Site US207 | Skokie | Illinois | 60077 | Recruiting |
| Investigative Site US205 | Plainfield | Indiana | 46168 | Recruiting |
| Investigative Site US264 | Lake Charles | Louisiana | 70601 | Recruiting |
| Investigative Site US266 | New Orleans | Louisiana | 70115 | Recruiting |
| Investigative Site US254 | Gambrills | Maryland | 21054 | Recruiting |
| Investigative Site US201 | Marriottsville | Maryland | 21104 | Recruiting |
| Investigative Site US253 | Milford | Massachusetts | 01757 | Recruiting |
| Investigative Site US227 | Needham | Massachusetts | 02492 | Recruiting |
| Investigative Site US268 | Worcester | Massachusetts | 01605 | Not yet recruiting |
| Investigative Site US238 | Ann Arbor | Michigan | 48103 | Recruiting |
| Investigative Site US230 | Auburn Hills | Michigan | 48326 | Recruiting |
| Investigative Site US251 | St Louis | Missouri | 63110-1010 | Recruiting |
| Investigative Site US271 | Wildwood | Missouri | 63040 | Recruiting |
| Investigative Site US212 | Missoula | Montana | 59804 | Recruiting |
| Investigative Site US216 | Las Vegas | Nevada | 89145 | Recruiting |
| Investigative Site US235 | Hoboken | New Jersey | 07030 | Recruiting |
| Investigative Site US217 | Albuquerque | New Mexico | 87102 | Recruiting |
| Investigative Site US219 | Brooklyn | New York | 11203 | Recruiting |
| Investigative Site US246 | Elmhurst | New York | 11373 | Recruiting |
| Investigative Site US269 | Fairport | New York | 14450 | Recruiting |
| Investigative Site US213 | Kew Gardens | New York | 11415 | Recruiting |
| Investigative Site US242 | New York | New York | 10075 | Recruiting |
| Investigative Site US245 | Rochester | New York | 14620 | Recruiting |
| Investigative Site US259 | Huntersville | North Carolina | 28078 | Recruiting |
| Investigative Site US263 | Winston-Salem | North Carolina | 27104 | Recruiting |
| Investigative Site US228 | Cleveland | Ohio | 44124 | Recruiting |
| Investigative Site US243 | Columbus | Ohio | 43213 | Recruiting |
| Investigative Site US249 | Columbus | Ohio | 43213 | Recruiting |
| Investigative Site US204 | Portland | Oregon | 97201 | Recruiting |
| Investigative Site US226 | Plymouth Meeting | Pennsylvania | 19462 | Recruiting |
| Investigative Site US256 | Bluffton | South Carolina | 29910 | Recruiting |
| Investigative Site US267 | Mt. Pleasant | South Carolina | 29464 | Recruiting |
| Investigative Site US255 | Austin | Texas | 78759 | Recruiting |
| Investigative Site US260 | Cypress | Texas | 77429 | Recruiting |
| Investigative Site US270 | Prosper | Texas | 75078 | Recruiting |
| Investigative Site US232 | Sugar Land | Texas | 77479 | Recruiting |
| Investigative Site US248 | Arlington | Virginia | 22206 | Recruiting |
| Investigative Site US209 | Danville | Virginia | 24541 | Recruiting |
| Investigative Site US229 | Norfolk | Virginia | 23502 | Recruiting |
| Investigative Site US265 | Seattle | Washington | 98105 | Recruiting |
| Investigative Site US224 | Spokane | Washington | 99202 | Recruiting |
| Investigative Site US210 | Milwaukee | Wisconsin | 53226 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06958211, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06958211 live on ClinicalTrials.gov.