A Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Public ClinicalTrials.gov record NCT06965413. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Placebo-controlled Phase 2 Trial to Assess Efficacy, Safety, and Tolerability of RO7204239 in Combination With Tirzepatide in Participants With Obesity or Overweight With At Least One Weight-related Comorbidity
Study identification
- NCT ID
- NCT06965413
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 285 participants
Conditions and interventions
Interventions
- RO7204239 Drug
- RO7204239 Matching Placebo Drug
- Tirzepatide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 4, 2025
- Primary completion
- Aug 23, 2026
- Completion
- Jul 22, 2027
- Last update posted
- Feb 11, 2026
2025 – 2027
United States locations
- U.S. sites
- 19
- U.S. states
- 11
- U.S. cities
- 19
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| K2 Medical Research-Winter Garden | Clermont | Florida | 34711 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Accellacare of Duly Health and Care | Oak Lawn | Illinois | 60453 | — |
| Rochester Clinical Research | Rochester | New York | 14609 | — |
| Accellacare of Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare of Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Accellacare of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Accellacare Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| NexGen Research | Lima | Ohio | 45801 | — |
| Accellacare of Bristol/ Internal Medicine & Pediatrics | Bristol | Tennessee | 37620 | — |
| Accellacare of Knoxville | Knoxville | Tennessee | 37912 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78731 | — |
| Juno Research, LLC | Houston | Texas | 77040 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Velocity Clinical Research (Impact Research Institute) | Waco | Texas | 76710 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06965413, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 11, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06965413 live on ClinicalTrials.gov.