INitiation and Titration of Guideline Directed Medical TheRApy in HearT Failure Cardiogenic Shock With ImpElla 5.5 for Cardiac Recovery

ClinicalTrials.gov ID: NCT06965504

Public ClinicalTrials.gov record NCT06965504. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 21, 2026, 8:02 AM EDT

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Official title

Initiation and Titration of Guideline Directed Medical Therapy in Heart Failure Cardiogenic Shock With Impella 5.5 for Cardiac Recovery: INTeGRATE

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study will evaluate the impact of a combined device-drug strategy with Impella 5.5 with best practices and optimized GDMT on heart recovery outcomes in patients with decompensated heart failure and cardiogenic shock.

Study identification

NCT ID: NCT06965504
Recruitment status: Recruiting
Study type: Interventional
Phase: Not applicable
Lead sponsor: Abiomed Inc.; Industry
Enrollment: 250 participants

Conditions and interventions

Conditions

Interventions

Impella 5.5 SmartAssist Device

Device

Eligibility (public fields only)

Age range: 18 Years to 80 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Oct 2, 2026 (Actual)
Primary completion: Dec 1, 2028 (Estimated)
Completion: Jun 1, 2029 (Estimated)
Last update posted: Oct 13, 2026

2026 – 2029

United States locations

U.S. sites: 17
U.S. states: 11
U.S. cities: 16

Facility	City	State	ZIP	Site status
Tampa General Hospital	Tampa	Florida	33606	Recruiting
Ascension St. Vincent	Indianapolis	Indiana	46260	Not yet recruiting
Abbott Northwestern	Minneapolis	Minnesota	555407	Recruiting
Barnes Jewish	St Louis	Missouri	63110	Not yet recruiting
Hackensack University Medical Center	Hackensack	New Jersey	07601	Not yet recruiting
Rutgers-Robert Wood Johnson Medical School	New Brunswick	New Jersey	08901	Not yet recruiting
New York Presbyterian - Columbia	New York	New York	10032	Not yet recruiting
Westchester Medical Center	Valhalla	New York	10595	Not yet recruiting
Atrium Health- Sanger Heart and Vascular Institute	Charlotte	North Carolina	28204	Not yet recruiting
Duke University	Durham	North Carolina	27710	Not yet recruiting
Wake Forest Baptist Medical Center	Winston-Salem	North Carolina	27157	Not yet recruiting
University of Pennsylvania Health System	Philadelphia	Pennsylvania	19104	Not yet recruiting
Allegheny General Hospital	Pittsburgh	Pennsylvania	15212	Not yet recruiting
UPMC Presbyterian	Pittsburgh	Pennsylvania	15213	Not yet recruiting
Centennial Medical Center	Nashville	Tennessee	32703	Not yet recruiting
Medical City Heart Hospital Dallas	Dallas	Texas	75243	Not yet recruiting
University of Utah	Salt Lake City	Utah	84132	Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06965504, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Oct 13, 2026 · Synced Oct 21, 2026

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The complete public registry record, listed eligibility criteria, and available contact information for NCT06965504 live on ClinicalTrials.gov.

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