Comparative Effectiveness of Migraine Preventive Medications: The APT Comparison Study
Public ClinicalTrials.gov record NCT06972056. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Comparative Effectiveness Study of Oral Medications Used for Migraine Prevention: The APT Comparison Study
Study identification
- NCT ID
- NCT06972056
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Mayo Clinic
- Other
- Enrollment
- 1,335 participants
Conditions and interventions
Conditions
Interventions
- Atogepant 60 mg Drug
- Propranolol 160 mg Drug
- Topiramate 100 mg Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 8, 2025
- Primary completion
- Feb 28, 2029
- Completion
- Nov 30, 2029
- Last update posted
- Apr 2, 2026
2025 – 2029
United States locations
- U.S. sites
- 23
- U.S. states
- 18
- U.S. cities
- 22
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Northern Arizona Healthcare | Flagstaff | Arizona | 86001 | Recruiting |
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | Recruiting |
| USC Keck | Los Angeles | California | 90033 | Not yet recruiting |
| Clinical Research Institute | Los Angeles | California | 90048 | Recruiting |
| Desert Physicians Medical Group | Palm Springs | California | 92262 | Recruiting |
| The Neurology Group | Pomona | California | 91767 | Recruiting |
| University of Colorado Anschutz Medical Campus | Aurora | Colorado | 80045 | Recruiting |
| Mayo Clinic Florida | Jacksonville | Florida | 32066 | Recruiting |
| Apple Med Research | Miami | Florida | 33126 | Recruiting |
| Clinical Trials of New England | Hyde Park | Massachusetts | 02136 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Washington University St Louis | St Louis | Missouri | 63110 | Recruiting |
| Advanced Research Institute Reno | Reno | Nevada | 89511 | Recruiting |
| JFK Neuroscience Institute | Edison | New Jersey | 08820 | Recruiting |
| Nuvance Health Institute | Kingston | New York | 12401 | Recruiting |
| Wake Forest University Health | Winston-Salem | North Carolina | 27157 | Recruiting |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | Not yet recruiting |
| Advanced Research Institute | Portland | Oregon | 97223 | Recruiting |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Vanderbilt Medical Center | Nashville | Tennessee | 37215 | Recruiting |
| DHR Health Headache Center | McAllen | Texas | 78504 | Not yet recruiting |
| Advanced Research Institute Ogden | Ogden | Utah | 84405 | Recruiting |
| West Virginia University | Morgantown | West Virginia | 26506 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06972056, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 2, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06972056 live on ClinicalTrials.gov.