Independent directory Public ClinicalTrials.gov records United States
Clinical Trials Finder
Objective public record navigation
ClinicalTrials.gov record
Recruiting Phase 3 Interventional

A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)

ClinicalTrials.gov ID: NCT06976203

Public ClinicalTrials.gov record NCT06976203. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

View official ClinicalTrials.gov record → Back to search
ClinicalTrials.gov public records Last synced Oct 17, 2026, 8:22 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for the Treatment of Cognitive Impairment Associated With Mild to Moderate Alzheimer's Disease (MINDSET 2)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of KarXT + KarX-EC for cognitive impairment in Alzheimer's Disease

Study identification

NCT ID
NCT06976203
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Bristol-Myers Squibb
Industry
Enrollment
586 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
60 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 21, 2025 (Actual)
Primary completion
Sep 11, 2028 (Estimated)
Completion
Feb 23, 2029 (Estimated)
Last update posted
Oct 8, 2026

2025 – 2029

United States locations

U.S. sites
31
U.S. states
13
U.S. cities
31
Facility City State ZIP Site status
Fullerton Neurology and Headache Center Fullerton California 92835 Recruiting
Irvine Clinical Research Irvine California 92614 Recruiting
Inglewood Clinical Los Angeles California 90056 Recruiting
Stanford Neuroscience Health Center Palo Alto California 94304 Recruiting
Local Institution - 0069 San Diego California 92103 Withdrawn
Research of the Rockies Colorado Springs Colorado 80919 Recruiting
Neuropsychiatric Research Center of Southwest Florida Fort Myers Florida 33912 Recruiting
Local Institution - 0086 Hallandale Florida 33009 Completed
Jacksonville Center for Clinical Research Jacksonville Florida 32216 Recruiting
K2 MEDICAL Research THE VILLAGES Lady Lake Florida 32159 Recruiting
Intercoastal Medical Group Sarasota Florida 34239 Recruiting
USF Health Byrd Alzheimer's Institute Tampa Florida 33613 Recruiting
Local Institution - 0129 The Villages Florida 32162 Not yet recruiting
Alzheimer's Research and Treatment Center Wellington Florida 33414 Recruiting
Great Lakes Clinical Trials - Andersonville Chicago Illinois 60640 Recruiting
Southern Illinois University School of Medicine Springfield Illinois 62702 Recruiting
Josephson Wallack Munshower Neurology, PC Indianapolis Indiana 46256 Recruiting
Local Institution - 0080 Watertown Massachusetts 02472 Not yet recruiting
QUEST Research Institute Farmington Hills Michigan 48334 Recruiting
Private Practice - Dr. Ronald Louis Schwartz Hattiesburg Mississippi 39401 Recruiting
Local Institution - 0119 Ridgewood New Jersey 07450 Withdrawn
The Cognitive and Research Center of New Jersey Springfield New Jersey 07081 Recruiting
Advanced Clinical Institute West Long Branch New Jersey 07764 Recruiting
Neurological Associates Albany Albany New York 12208 Recruiting
Dent Neurosciences Research Center, Inc Amherst New York 14226 Recruiting
University at Buffalo - UBMD Neurology Buffalo New York 14203 Recruiting
Local Institution - 0078 Lake Success New York 11042 Withdrawn
Keystone Clinical Studies Plymouth Meeting Pennsylvania 19462 Recruiting
Local Institution - 0081 Dallas Texas 75231 Not yet recruiting
Central Texas Neurology Consultants, PA Round Rock Texas 78681 Recruiting
Local Institution - 0076 Renton Washington 98057 Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 96 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06976203, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 8, 2026 · Synced Oct 17, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06976203 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →