A Research Study Comparing Different Doses of CDR132L With Placebo on the Structure and Function of the Heart in People With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

ClinicalTrials.gov ID: NCT06979362

Public ClinicalTrials.gov record NCT06979362. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 6, 2026, 2:50 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2, Multicentre, Randomised, Double-blind, Placebo-controlled Safety and Efficacy Study of CDR132L on Reverse Cardiac Remodelling in Participants With Heart Failure With Preserved Ejection Fraction and Left Ventricular Hypertrophy

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will look into how CDR132L (a potential new medicine) works on the structure and function of the heart in people living with heart failure. Participants will either get CDR132L or placebo (a medicine which has no effect on the body), which treatment the participants get is decided by chance. The study will last for about 60 weeks.

Study identification

NCT ID: NCT06979362
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Novo Nordisk A/S; Industry
Enrollment: 200 participants

Conditions and interventions

Conditions

Heart Failure

Interventions

CDR132L Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 40 Years to 84 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 26, 2025
Primary completion: Nov 15, 2027
Completion: Jul 24, 2028
Last update posted: Aug 4, 2026

2025 – 2028

United States locations

U.S. sites: 29
U.S. states: 16
U.S. cities: 27

Facility	City	State	ZIP	Site status
Univ of Alabama Birmingham	Birmingham	Alabama	35233	Recruiting
TMC Hlthcr Clin Res Office	Tucson	Arizona	85712	Not yet recruiting
Pima Heart and Vascular	Tucson	Arizona	85741	Not yet recruiting
Valley Clinical Trials	Covina	California	91723	Recruiting
UCSD NAFLD Research Center	La Jolla	California	92037	Recruiting
Valley Clinical Trials	Northridge	California	91325	Recruiting
University of California, San Francisco	San Francisco	California	94110	Recruiting
University of California San Francisco UCSF	San Francisco	California	94143	Recruiting
Harbor-UCLA Medical Center	Torrance	California	90502	Recruiting
Univ of Colorado at Denver	Aurora	Colorado	80045	Not yet recruiting
Inpatient Research Clinic LLC	Miami Lakes	Florida	33014	Recruiting
AdventHealth Orlando	Orlando	Florida	32803	Not yet recruiting
Guardian Research Org LLC	Winter Park	Florida	32792	Not yet recruiting
UofL Health Care Outpatient	Louisville	Kentucky	40202	Not yet recruiting
Henry Ford Hospital_Detroit	Detroit	Michigan	48202	Recruiting
University of Minnesota_Minneapolis_1	Minneapolis	Minnesota	55455	Completed
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Icahn Sch of Med-Mt Sinai Hosp	New York	New York	10029	Not yet recruiting
Duke University	Durham	North Carolina	27710	Recruiting
Providence St. Vincent Heart	Portland	Oregon	97225	Completed
Abington Memorial Hospital	Abington	Pennsylvania	19001	Completed
Capital Area Research LLC	Camp Hill	Pennsylvania	17011	Recruiting
Vanderbilt University Medical Center	Nashville	Tennessee	37232	Recruiting
Amarillo Medical Specialists	Amarillo	Texas	79124	Not yet recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390-8830	Recruiting
Texama Medical Center	Denison	Texas	75020	Not yet recruiting
East Texas Cardiology PA	Houston	Texas	77002	Recruiting
Inova Heart and Vascular Institute	Falls Church	Virginia	22042	Recruiting
Sentara Bayside Hospital	Norfolk	Virginia	23507-1904	Completed

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 82 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT06979362, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 4, 2026 · Synced Sep 6, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06979362 live on ClinicalTrials.gov.

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