A Study of MK-5684 in People With Certain Solid Tumors (MK-5684-015/OMAHA-015)
Public ClinicalTrials.gov record NCT06979596. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Open-label, Phase 2 Basket Study of MK-5684 in Participants With Selected Solid Tumors (OMAHA-015)
Study identification
- NCT ID
- NCT06979596
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 250 participants
Conditions and interventions
Conditions
Interventions
- Dexamethasone/Dexamethasone acetate Drug
- Exemestane Drug
- Fludrocortisone/ Fludrocortisone acetate Drug
- Fulvestrant Drug
- Letrozole Drug
- Megestrol acetate/Medroxyprogesterone acetate Drug
- Opevesostat Drug
- Rescue Medications Drug
- Tamoxifen Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 10, 2025
- Primary completion
- Nov 3, 2027
- Completion
- Nov 3, 2027
- Last update posted
- Apr 12, 2026
2025 – 2027
United States locations
- U.S. sites
- 7
- U.S. states
- 6
- U.S. cities
- 7
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Alaska Womens Cancer Care ( Site 0037) | Anchorage | Alaska | 99508 | Recruiting |
| Mount Sinai Cancer Center ( Site 0009) | Miami Beach | Florida | 33140 | Recruiting |
| TRIALS 365 ( Site 0022) | Shreveport | Louisiana | 71103 | Recruiting |
| Mary Lanning Healthcare ( Site 0019) | Hastings | Nebraska | 68901 | Recruiting |
| John Theurer Cancer Center at Hackensack University Medical Center ( Site 0021) | Hackensack | New Jersey | 07601 | Recruiting |
| Baylor College of Medicine Medical Center ( Site 0004) | Houston | Texas | 77030 | Recruiting |
| Mays Cancer Center ( Site 0039) | San Antonio | Texas | 78229 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06979596, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06979596 live on ClinicalTrials.gov.