A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD
Public ClinicalTrials.gov record NCT06981078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Randomized, Double-blind, Placebo-controlled, Parallel-Group Study to Assess Efficacy and Safety of Verekitug (UPB-101) in Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Study identification
- NCT ID
- NCT06981078
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Upstream Bio Inc.
- Industry
- Enrollment
- 666 participants
Conditions and interventions
Conditions
Interventions
- Placebo Other
- Verekitug Drug
Other · Drug
Eligibility (public fields only)
- Age range
- 40 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 1, 2025
- Primary completion
- Mar 31, 2028
- Completion
- Jun 30, 2028
- Last update posted
- Feb 12, 2026
2025 – 2028
United States locations
- U.S. sites
- 32
- U.S. states
- 12
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Kern Research Inc. | Bakersfield | California | 93301 | Active, not recruiting |
| PulmoCrit Associates | Encino | California | 91436 | Active, not recruiting |
| Torrance Clinical Research Institute | Lomita | California | 90717-2101 | Active, not recruiting |
| Dream Team Clinical Research | Pomona | California | 91767 | Active, not recruiting |
| Apex Clinical Research | San Diego | California | 92120 | Active, not recruiting |
| Allianz Research Institute | Westminster | California | 92683 | Active, not recruiting |
| Allianz Research Institute | Aurora | Colorado | 80014 | Withdrawn |
| D&H Doral Research Center, LLC | Doral | Florida | 33122 | Active, not recruiting |
| Qway Research, LLC | Hialeah | Florida | 33010 | Active, not recruiting |
| Finlay Medical Research | Miami | Florida | 33126 | Active, not recruiting |
| Research Institute of South Florida | Miami | Florida | 33173 | Active, not recruiting |
| Florida Institute for Clinical Research,LLC | Orlando | Florida | 32825 | Active, not recruiting |
| Velocity Clinical Research-Savannah - Internal Medicine | Savannah | Georgia | 31406 | Active, not recruiting |
| Christie Clinic, LLC | Champaign | Illinois | 61820 | Active, not recruiting |
| The Iowa Clinic | West Des Moines | Iowa | 50266 | Active, not recruiting |
| Velocity Clinical Research-Rockville | Rockville | Maryland | 20854 | Active, not recruiting |
| Chesapeake Clinical Research, Inc | White Marsh | Maryland | 21162 | Active, not recruiting |
| HealthPartners | Saint Paul | Minnesota | 55130 | Active, not recruiting |
| American Health Research, Inc. | Charlotte | North Carolina | 28277 | Active, not recruiting |
| Velocity Clinical Research, Anderson | Anderson | South Carolina | 29621 | Active, not recruiting |
| SleepMed Inc. | Columbia | South Carolina | 29201 | Active, not recruiting |
| Velocity Clinical Research, Gaffney | Greenville | South Carolina | 29615 | Active, not recruiting |
| Velocity Clinical Research, Spartanburg - Pulmonology | Spartanburg | South Carolina | 29303 | Active, not recruiting |
| Velocity Clinical Research- Union | Union | South Carolina | 29379 | Active, not recruiting |
| Elligo Health Research, Inc. | Austin | Texas | 78738 | Withdrawn |
| El Paso Pulmonary Association | El Paso | Texas | 79902 | Active, not recruiting |
| Victorium Clinical Research | Houston | Texas | 77024 | Active, not recruiting |
| Synergy Groups Medical LLC | Houston | Texas | 77036 | Active, not recruiting |
| Synergy Groups Medical LLC | Houston | Texas | 77061 | Active, not recruiting |
| Metroplex Pulmonary and Sleep Center | McKinney | Texas | 75069 | Active, not recruiting |
| Synergy Groups Medical LLC | Missouri City | Texas | 77459 | Active, not recruiting |
| Velocity Clinical Research - Suffolk | Suffolk | Virginia | 23435 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 293 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06981078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 12, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06981078 live on ClinicalTrials.gov.