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Active, not recruiting Phase 2 Interventional

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

ClinicalTrials.gov ID: NCT06981078

Public ClinicalTrials.gov record NCT06981078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 6, 2026, 11:54 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2b Randomized, Double-blind, Placebo-controlled, Parallel-Group Study to Assess Efficacy and Safety of Verekitug (UPB-101) in Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of verekitug (UPB-101) in participants with moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD), an inflammatory lung disease.

Study identification

NCT ID
NCT06981078
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Upstream Bio Inc.
Industry
Enrollment
666 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
40 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2025
Primary completion
Sep 30, 2027
Completion
Oct 31, 2027
Last update posted
Jul 19, 2026

2025 – 2027

United States locations

U.S. sites
29
U.S. states
10
U.S. cities
26
Facility City State ZIP Site status
Kern Research Inc. Bakersfield California 93301
PulmoCrit Associates Encino California 91436
Torrance Clinical Research Institute Lomita California 90717-2101
Dream Team Clinical Research Pomona California 91767
Apex Clinical Research San Diego California 92120
Allianz Research Institute Westminster California 92683
D&H Doral Research Center, LLC Doral Florida 33122
Qway Research, LLC Hialeah Florida 33010
Finlay Medical Research Miami Florida 33126
MplusM - ITB Research Miami Florida 33173
Florida Institute for Clinical Research,LLC Orlando Florida 32825
Velocity Clinical Research-Savannah - Internal Medicine Savannah Georgia 31406
Christie Clinic, LLC Champaign Illinois 61820
Velocity Clinical Research-Rockville Rockville Maryland 20854
Chesapeake Clinical Research, Inc White Marsh Maryland 21162
HealthPartners Saint Paul Minnesota 55130
American Health Research, Inc. Charlotte North Carolina 28277
Velocity Clinical Research, Anderson Anderson South Carolina 29621
SleepMed Inc. Columbia South Carolina 29201
Velocity Clinical Research, Gaffney Greenville South Carolina 29615
Velocity Clinical Research, Spartanburg - Pulmonology Spartanburg South Carolina 29303
Velocity Clinical Research- Union Union South Carolina 29379
El Paso Pulmonary Association El Paso Texas 79902
Victorium Clinical Research Houston Texas 77024
Synergy Groups Medical LLC Houston Texas 77036
Synergy Groups Medical LLC Houston Texas 77061
Metroplex Pulmonary and Sleep Center McKinney Texas 75069
Synergy Groups Medical LLC Missouri City Texas 77459
Velocity Clinical Research - Suffolk Suffolk Virginia 23435

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 213 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06981078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 19, 2026 · Synced Sep 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06981078 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →