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Recruiting Phase 1 Interventional

A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors

ClinicalTrials.gov ID: NCT06983743

Public ClinicalTrials.gov record NCT06983743. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 25, 2026, 4:16 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1 First-in-Human Open-Label Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Efficacy of ERAS-0015 Monotherapy and in Combination in Patients Advanced Solid Tumors

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of the study is to assess whether the study drug, ERAS-0015, is safe and tolerable when administered to patients with advanced or metastatic solid tumors with certain RAS mutations. ERAS-0015 will be given alone or in combination with other treatments.

Study identification

NCT ID
NCT06983743
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Erasca, Inc.
Industry
Enrollment
600 participants

Conditions and interventions

Eligibility (public fields only)

Age range
18 Years to 99 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 4, 2025
Primary completion
Apr 30, 2028
Completion
Nov 30, 2028
Last update posted
Aug 31, 2026

2025 – 2028

United States locations

U.S. sites
9
U.S. states
7
U.S. cities
9
Facility City State ZIP Site status
Providence Medical Group Santa Rosa California 95403 Recruiting
University of Colorado Aurora Colorado 80045 Recruiting
Florida Cancer Specalists Sarasota Florida 34232 Recruiting
Moffitt Cancer Center Tampa Florida 33612 Recruiting
Massachusetts General Hospital (MG) Boston Massachusetts 02114 Recruiting
Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
The University of Texas MD Anderson Cancer Center Houston Texas 77030 Recruiting
University of Texas at Tyler Tyler Texas 75701 Recruiting
NEXT Virginia Fairfax Virginia 22031 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06983743, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 31, 2026 · Synced Sep 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06983743 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →