ClinicalTrials.gov record
A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
ClinicalTrials.gov ID: NCT06990399
Public ClinicalTrials.gov record NCT06990399. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Sham-controlled, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tabirafusp Alfa (KSI-101) in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Study identification
- NCT ID
- NCT06990399
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Kodiak Sciences Inc
- Industry
- Enrollment
- 600 participants
Conditions and interventions
Conditions
Interventions
- KSI-101 Drug
- Sham Comparator Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 29, 2025
- Primary completion
- Mar 31, 2027
- Completion
- Oct 31, 2027
- Last update posted
- May 17, 2026
2025 – 2027
United States locations
- U.S. sites
- 55
- U.S. states
- 24
- U.S. cities
- 50
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AZ Retina & Vitreous Consultants | Phoenix | Arizona | 85016 | Recruiting |
| Research Network Arizona | Scottsdale | Arizona | 85255 | Recruiting |
| California Retina Consultants (Bakersfield) | Bakersfield | California | 93309 | Recruiting |
| Global Research Management, Inc. | Glendale | California | 91204 | Recruiting |
| UCSD/Jacobs Retina Center | La Jolla | California | 92093 | Recruiting |
| UCLA Stein Eye Institute | Los Angeles | California | 90095 | Recruiting |
| California Retina Consultants (Oxnard) | Oxnard | California | 93036 | Recruiting |
| Stanford Byers Eye Institute | Palo Alto | California | 94303 | Not yet recruiting |
| California Eye Specialists Medical Group, Inc. | Pasadena | California | 91107 | Recruiting |
| California Eye Specialists Medical Group, Inc. | Redlands | California | 92373 | Recruiting |
| Retina Consultants of Southern California | Redlands | California | 92374 | Recruiting |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95841 | Recruiting |
| Retina Specialists of Colorado (RSC) | Denver | Colorado | 80222 | Withdrawn |
| Rocky Mountain Uveitis | Denver | Colorado | 80246 | Recruiting |
| Coastal Eye Surgeons | Greenwich | Connecticut | 06830 | Recruiting |
| Retina Consultants, PC | Manchester | Connecticut | 06042 | Recruiting |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | Recruiting |
| Florida Eye Clinic | Altamonte Springs | Florida | 32701 | Not yet recruiting |
| Retina Group of Florida (Ft. Lauderdale) | Fort Lauderdale | Florida | 33308 | Recruiting |
| Retina Vitreous Associates of Florida (St. Petersburg) | St. Petersburg | Florida | 33711 | Recruiting |
| Retina Associates, LTD | Elmhurst | Illinois | 60126 | Recruiting |
| Associated Vitreoretinal and Uveitis Consultants LLC | Carmel | Indiana | 46032 | Recruiting |
| Midwest Eye Institute | Carmel | Indiana | 46032 | Recruiting |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | Recruiting |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | Recruiting |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | Recruiting |
| The Retina Institute | St Louis | Missouri | 63128 | Recruiting |
| St. Mary's Eye Surgery Center (Metropolitan Eye Research and Surgery Institute) | Palisades Park | New Jersey | 07650 | Recruiting |
| Eye Associates of New Mexico, Vision Research Center | Albuquerque | New Mexico | 87109 | Not yet recruiting |
| Retina Associates of New York, P.C. | New York | New York | 10075 | Recruiting |
| North Carolina Retina Associates (Cary) | Cary | North Carolina | 27511 | Recruiting |
| North Carolina Retina Associates (Wake Forest) | Wake Forest | North Carolina | 27587 | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | 44195 | Not yet recruiting |
| Ohio State University | Columbus | Ohio | 43212 | Recruiting |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | Recruiting |
| Erie Retina Research | Erie | Pennsylvania | 16507 | Recruiting |
| Vision Research Solutions | Philadelphia | Pennsylvania | 19141 | Withdrawn |
| Charleston Neuroscience Institute, LLC (Charleston) | Charleston | South Carolina | 29414 | Recruiting |
| Palmetto Retina Center (West Columbia) | West Columbia | South Carolina | 29169 | Recruiting |
| Ophthalmology Ltd | Sioux Falls | South Dakota | 57108 | Recruiting |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt Eye Institute | Nashville | Tennessee | 37232 | Recruiting |
| Retina Research Institute of Texas | Abilene | Texas | 70606 | Recruiting |
| Austin Retina Associates, PLLC (Austin) | Austin | Texas | 78705 | Recruiting |
| UT Austin | Austin | Texas | 78712 | Not yet recruiting |
| Retina Consultants of Texas (Bellaire) | Bellaire | Texas | 77401 | Recruiting |
| Texas Retina Center | Houston | Texas | 77030 | Recruiting |
| Retina Consultants of Texas (Katy) | Katy | Texas | 77494 | Recruiting |
| Texas Retina Associates (Plano) | Plano | Texas | 75075 | Recruiting |
| Austin Retina Associates, PLLC (Round Rock) | Round Rock | Texas | 78681 | Recruiting |
| Retina Consultants of Texas (San Antonio) | San Antonio | Texas | 78240 | Recruiting |
| Retina Consultants of Texas (Woodlands) | The Woodlands | Texas | 77384 | Recruiting |
| Pacific Northwest Retina (Bellevue) | Bellevue | Washington | 98004 | Recruiting |
| Pacific Northwest Retina (Silverdale) | Silverdale | Washington | 98383 | Recruiting |
| Eye Clinic of Wisconsin | Wausau | Wisconsin | 54403 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06990399, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 17, 2026 · Synced May 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06990399 live on ClinicalTrials.gov.