A Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-101 in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Public ClinicalTrials.gov record NCT06990399. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-masked, Sham-controlled, Multicenter, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal Tabirafusp Alfa (KSI-101) in Participants With Macular Edema Secondary to Inflammation (MESI) - PEAK
Study identification
- NCT ID
- NCT06990399
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Kodiak Sciences Inc
- Industry
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Interventions
- KSI-101 Drug
- Sham Comparator Other
Drug · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 29, 2025
- Primary completion
- Jan 31, 2026
- Completion
- Jun 30, 2027
- Last update posted
- Sep 9, 2025
2025 – 2027
United States locations
- U.S. sites
- 33
- U.S. states
- 16
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Network Arizona | Scottsdale | Arizona | 85255 | Not yet recruiting |
| Global Research Management, Inc. | Glendale | California | 91204 | Not yet recruiting |
| UCLA Stein Eye Institute | Los Angeles | California | 90095 | Not yet recruiting |
| Stanford Byers Eye Institute | Palo Alto | California | 94303 | Not yet recruiting |
| California Eye Specialists Medical Group, Inc. | Pasadena | California | 91107 | Recruiting |
| California Eye Specialists Medical Group, Inc. | Redlands | California | 92373 | Not yet recruiting |
| Retina Consultants of Southern California | Redlands | California | 92374 | Not yet recruiting |
| Retinal Consultants Medical Group Inc | Sacramento | California | 95841 | Recruiting |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | Recruiting |
| Retina Group of Florida (Ft. Lauderdale) | Fort Lauderdale | Florida | 33308 | Not yet recruiting |
| Associated Vitreoretinal and Uveitis Consultants LLC | Carmel | Indiana | 46032 | Recruiting |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | Recruiting |
| Retina Consultants of Minnesota | Saint Louis Park | Minnesota | 55416 | Not yet recruiting |
| The Retina Institute | St Louis | Missouri | 63128 | Not yet recruiting |
| Retina Associates of New York, P.C. | New York | New York | 10075 | Not yet recruiting |
| North Carolina Retina Associates (Cary) | Cary | North Carolina | 27511 | Not yet recruiting |
| North Carolina Retina Associates (Wake Forest) | Wake Forest | North Carolina | 27587 | Not yet recruiting |
| Cascade Medical Research Institute | Springfield | Oregon | 97477 | Recruiting |
| Erie Retina Research | Erie | Pennsylvania | 16507 | Recruiting |
| Charleston Neuroscience Institute, LLC (Charleston) | Charleston | South Carolina | 29414 | Not yet recruiting |
| Palmetto Retina Center (West Columbia) | West Columbia | South Carolina | 29169 | Recruiting |
| Vanderbilt Eye Institute | Nashville | Tennessee | 37232 | Not yet recruiting |
| Austin Retina Associates, PLLC (Austin) | Austin | Texas | 78705 | Recruiting |
| UT Austin | Austin | Texas | 78712 | Not yet recruiting |
| Retina Consultants of Texas (Bellaire) | Bellaire | Texas | 77401 | Not yet recruiting |
| Texas Retina Center | Houston | Texas | 77030 | Not yet recruiting |
| Retina Consultants of Texas (Katy) | Katy | Texas | 77494 | Recruiting |
| Texas Retina Associates (Plano) | Plano | Texas | 75075 | Recruiting |
| Austin Retina Associates, PLLC (Round Rock) | Round Rock | Texas | 78681 | Not yet recruiting |
| Retina Consultants of Texas (San Antonio) | San Antonio | Texas | 78240 | Recruiting |
| Retina Consultants of Texas (Woodlands) | The Woodlands | Texas | 77384 | Recruiting |
| Pacific Northwest Retina (Bellevue) | Bellevue | Washington | 98004 | Not yet recruiting |
| Pacific Northwest Retina (Silverdale) | Silverdale | Washington | 98383 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06990399, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2025 · Synced May 9, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06990399 live on ClinicalTrials.gov.