An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Public ClinicalTrials.gov record NCT06991556. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Randomized, Open-label, Multi-center Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)
Study identification
- NCT ID
- NCT06991556
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Novartis Pharmaceuticals
- Industry
- Enrollment
- 150 participants
Conditions and interventions
Conditions
Interventions
- Abiraterone Drug
- Enzalutamide Drug
- JSB462 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 6, 2025
- Primary completion
- Mar 28, 2032
- Completion
- Oct 18, 2035
- Last update posted
- Apr 30, 2026
2025 – 2035
United States locations
- U.S. sites
- 20
- U.S. states
- 17
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California San Diego - Moores Cancer Center | La Jolla | California | 92093-0658 | Recruiting |
| Saint Johns Cancer Institute | Santa Monica | California | 90404 | Recruiting |
| Rocky Mountain Cancer Centers | Denver | Colorado | 80218 | Recruiting |
| Yale Cancer Center | New Haven | Connecticut | 06520 | Recruiting |
| Advanced Urology Ins Daytona Beach | Daytona Beach | Florida | 32114 | Recruiting |
| Emory University School of Medicine-Winship Cancer Institute | Atlanta | Georgia | 30322 | Recruiting |
| Associated Urological Specialists | Chicago Ridge | Illinois | 60415 | Recruiting |
| American Oncology Partners PA Center for Cancer and Blood Disorders | Bethesda | Maryland | 20817 | Recruiting |
| Mass General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Michigan Institute of Urology | West Bloomfield | Michigan | 48322 | Recruiting |
| XCancer Omaha LLC | Omaha | Nebraska | 68130 | Recruiting |
| Perlmutter Cancer Centre | New York | New York | 10016 | Recruiting |
| Associated Med Professionals of NY | Syracuse | New York | 13210 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Fox Chase Cancer Center | Philadelphia | Pennsylvania | 19111 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Tennessee Oncology | Nashville | Tennessee | 37203 | Recruiting |
| Urology San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
| Fred Hutch Cancer Research | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 45 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06991556, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 30, 2026 · Synced May 4, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06991556 live on ClinicalTrials.gov.