Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Public ClinicalTrials.gov record NCT06995677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Multicenter, Open-Label Study Evaluating the Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer (SURF302)
Study identification
- NCT ID
- NCT06995677
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Tyra Biosciences, Inc
- Industry
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Interventions
- TYRA-300 50mg Drug
- TYRA-300 60mg Drug
- TYRA-300 Dose TBD Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2025
- Primary completion
- Jan 31, 2028
- Completion
- Aug 31, 2028
- Last update posted
- May 7, 2026
2025 – 2028
United States locations
- U.S. sites
- 25
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Urology Centers of Alabama | Homewood | Alabama | 35209 | Recruiting |
| Arkansas Urology | Little Rock | Arkansas | 72211 | Recruiting |
| Tri Valley Urology - Murrieta | Murrieta | California | 92562 | Recruiting |
| Om Research LLC | San Diego | California | 92123 | Recruiting |
| Associated Urological Specialists | Chicago Ridge | Illinois | 60415 | Recruiting |
| Duly Health and Care | Lisle | Illinois | 60532 | Recruiting |
| First Urology | Jeffersonville | Indiana | 47130 | Recruiting |
| University of Kansas Medical Center (KUMC) | Kansas City | Kansas | 66160 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21205 | Recruiting |
| Atlantic Health System | Morristown | New Jersey | 07960 | Recruiting |
| Memorial Sloan Kettering Cancer Center - Sidney Kimmel Center for Prostate and Urologic Cancers | New York | New York | 10065 | Recruiting |
| Associated Medical Professionals of NY | Syracuse | New York | 13210 | Recruiting |
| The Bronx Veterans Medical Research Foundation, Inc. | The Bronx | New York | 10468 | Recruiting |
| Duke Cancer Institute | Durham | North Carolina | 27705 | Recruiting |
| Associate Urologist of North Carolina | Raleigh | North Carolina | 27612 | Recruiting |
| Oregon Urology Institute | Springfield | Ohio | 97477 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Keystone Urology Specialists | Lancaster | Pennsylvania | 17604 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Lowcounty Urology Clinics, P.A. | North Charleston | South Carolina | 29406 | Recruiting |
| Conrad Pearson-Memphis | Germantown | Tennessee | 38138 | Recruiting |
| Urology Associates PC | Nashville | Tennessee | 37209 | Recruiting |
| Urology Austin | Austin | Texas | 78759 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Urology San Antonio | San Antonio | Texas | 78229 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06995677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 7, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06995677 live on ClinicalTrials.gov.