Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer
Public ClinicalTrials.gov record NCT06995677. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Multicenter, Open-Label Study Evaluating the Efficacy and Safety of TYRA-300 in Participants With FGFR3 Altered Low Grade, Intermediate Risk Non-Muscle Invasive Bladder Cancer (SURF302)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 2 Study of TYRA-300 in FGFR3 Altered Low Grade, Intermediate Risk NMIBC
Study identification
- NCT ID
- NCT06995677
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 90 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 26, 2025
- Primary completion
- Jan 31, 2028
- Completion
- Aug 31, 2028
- Last update posted
- Aug 5, 2026
2025 – 2028
United States locations
- U.S. sites
- 35
- U.S. states
- 17
- U.S. cities
- 33
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Urology Centers of Alabama | Homewood | Alabama | 35209 | Recruiting |
| Arkansas Urology | Little Rock | Arkansas | 72211 | Recruiting |
| Tri Valley Urology - Murrieta | Murrieta | California | 92562 | Recruiting |
| Eisenhower Medical Associates | Rancho Mirage | California | 92270 | Recruiting |
| Om Research LLC | San Diego | California | 92123 | Recruiting |
| Associated Urological Specialists | Chicago Ridge | Illinois | 60415 | Recruiting |
| Duly Health and Care | Lisle | Illinois | 60532 | Recruiting |
| Urology of Indiana | Greenwood | Indiana | 46143 | Recruiting |
| First Urology | Jeffersonville | Indiana | 47130 | Recruiting |
| University of Kansas Medical Center (KUMC) | Kansas City | Kansas | 66160 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21205 | Recruiting |
| Greater Boston Urology | Plymouth | Massachusetts | 02360 | Recruiting |
| Specialty Clinical Research of St. Louis | St Louis | Missouri | 63141 | Recruiting |
| Atlantic Health System | Morristown | New Jersey | 07960 | Recruiting |
| New Jersey Urology, LLC (Summit Health - Washington Township) | Voorhees Township | New Jersey | 08043 | Recruiting |
| NYU Langone Health | New York | New York | 10016 | Recruiting |
| Memorial Sloan Kettering Cancer Center - Sidney Kimmel Center for Prostate and Urologic Cancers | New York | New York | 10065 | Recruiting |
| Associated Medical Professionals of NY | Syracuse | New York | 13210 | Recruiting |
| State University of New York (SUNY) Upstate Medical University | Syracuse | New York | 13210 | Recruiting |
| The Bronx Veterans Medical Research Foundation, Inc. | The Bronx | New York | 10468 | Recruiting |
| Duke Cancer Institute | Durham | North Carolina | 27705 | Recruiting |
| Associate Urologist of North Carolina | Raleigh | North Carolina | 27612 | Recruiting |
| The James at Brain and Spine Hospital (OSU) | Columbus | Ohio | 43210 | Recruiting |
| Oregon Urology Institute | Springfield | Ohio | 97477 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Keystone Urology Specialists | Lancaster | Pennsylvania | 17604 | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Lowcounty Urology Clinics, P.A. | North Charleston | South Carolina | 29406 | Recruiting |
| Conrad Pearson-Memphis | Germantown | Tennessee | 38138 | Recruiting |
| Urology Associates PC | Nashville | Tennessee | 37209 | Recruiting |
| Urology Austin | Austin | Texas | 78759 | Recruiting |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | Recruiting |
| Baylor College of Medicine | Houston | Texas | 77030 | Recruiting |
| Urology San Antonio | San Antonio | Texas | 78229 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 12 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06995677, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 5, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06995677 live on ClinicalTrials.gov.