A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
Public ClinicalTrials.gov record NCT06995729. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 1, MULTICENTER, OPEN-LABEL, SINGLE-DOSE STUDY TO EVALUATE THE SAFETY, TOLERABILITY AND PHARMACOKINETICS OF ZAVEGEPANT IN CHILDREN 6 TO LESS THAN 12 YEARS OF AGE WITH HISTORY OF MIGRAINE
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it. This study is seeking participants who: * Are children aged between 6 and less than 12 years old * Have had migraine for at least 6 months. * Weigh more than 15 kilograms All participants in this study will receive zavegepant as a nasal spray once (one spray into one nostril). The dose of the study medicine that each participant receives will depend on how much the participant weighs. The study will look at the experiences of the participants receiving the study medicine and collect data to better understand the possible benefits and unwanted effects of different doses of the study medicine. Participants will take part in this study for up to 10 weeks. During this time, they will have 3 study visits at the study clinic, and 2 follow-up phone calls.
Study identification
- NCT ID
- NCT06995729
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 16 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years to 11 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 16, 2025 (Actual)
- Primary completion
- Aug 12, 2027 (Estimated)
- Completion
- Aug 12, 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2025 – 2027
United States locations
- U.S. sites
- 14
- U.S. states
- 11
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Velocity Clinical Research, Washington DC | Washington D.C. | District of Columbia | 20016 | Recruiting |
| Coastal Heritage Clinical Research | Hinesville | Georgia | 31313 | Recruiting |
| Clinical Research Institute | Minneapolis | Minnesota | 55402 | Recruiting |
| Children's Hospital & Medical Center | Omaha | Nebraska | 68114 | Recruiting |
| True North Neurology | Port Jefferson Station | New York | 11776 | Recruiting |
| Accellacare - Piedmont | Statesville | North Carolina | 28625 | Recruiting |
| Accellacare of Piedmont HealthCare | Statesville | North Carolina | 28625 | Recruiting |
| Accellacare US Inc. | Winston-Salem | North Carolina | 27103 | Recruiting |
| Cincinnati Children's Hospital Medical Center | Cincinnati | Ohio | 45229 | Recruiting |
| Central States Research | Tulsa | Oklahoma | 74136 | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Cedar Health Research | Dallas | Texas | 75251 | Active, not recruiting |
| Wasatch Clinical Research, LLC | Salt Lake City | Utah | 84107 | Active, not recruiting |
| Granger Medical Holladay - Holladay Clinic | Salt Lake City | Utah | 84117 | Active, not recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06995729, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 22, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06995729 live on ClinicalTrials.gov.