Study to Assess the Injection Burden, Adverse Events, Change in Disease Activity, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec in Adult Participants With Neovascular Age-Related Macular Degeneration (nAMD)

ClinicalTrials.gov ID: NCT07007065

Public ClinicalTrials.gov record NCT07007065. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 29, 2026, 9:04 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Controlled, Partially Masked, Phase 3b Study to Assess the Injection Burden, Efficacy, Safety, and Long-Term Preservation of Visual Acuity of Surabgene Lomparvovec (ABBV-RGX-314) in a Real-World Context in Subjects With Neovascular Age-Related Macular Degeneration (nAMD)

Study identification

NCT ID: NCT07007065
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: AbbVie; Industry
Enrollment: 561 participants

Conditions and interventions

Conditions

Neovascular Age-related Macular Degeneration

Interventions

Ranibizumab Control Drug
Surabgene Lomparvovec (ABBV-RGX-314) Drug

Drug

Eligibility (public fields only)

Age range: 50 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 4, 2025
Primary completion: Feb 28, 2033
Completion: Feb 28, 2033
Last update posted: Apr 13, 2026

2025 – 2033

United States locations

U.S. sites: 37
U.S. states: 17
U.S. cities: 36

Facility	City	State	ZIP	Site status
Barnet Dulaney Perkins Eye Centers /ID# 279265	Mesa	Arizona	85206	Recruiting
American Vision Partners /ID# 264615	Sun City	Arizona	85351	Recruiting
Retinal Diagnostic Center /ID# 263054	Campbell	California	95008	Recruiting
The Retina Partners /ID# 263265	Encino	California	91436	Recruiting
Retina Associates of Southern California /ID# 263056	Huntington Beach	California	92647	Recruiting
Retina Consultants of San Diego /ID# 264026	Poway	California	92064-2530	Recruiting
Retinal Consultants - Sacramento - Greenback Lane /ID# 263983	Sacramento	California	95841	Recruiting
Orange County Retina Medical Group /ID# 266612	Santa Ana	California	92705	Recruiting
Retina Consultants of Southern Colorado /ID# 263284	Colorado Springs	Colorado	80909	Recruiting
Colorado Retina Associates /ID# 263247	Lakewood	Colorado	80228	Recruiting
Advanced Vision Surgery Center /ID# 264208	Longmont	Colorado	80503	Recruiting
Advanced Research, LLC /ID# 276526	Deerfield Beach	Florida	33064-1346	Recruiting
Retina Vitreous Consultants LLP business DBA as Retina Group of Florida /ID# 264631	Fort Myers	Florida	33917	Recruiting
Florida Retina Institute - Lake Mary /ID# 263288	Lake Mary	Florida	32746	Recruiting
Center for Retina and Macular Disease /ID# 264201	Winter Haven	Florida	33880	Recruiting
Southeast Retina Center /ID# 263264	Augusta	Georgia	30909	Recruiting
Springfield Clinic Main Campus /ID# 265202	Springfield	Illinois	62703-2403	Recruiting
Midwest Eye Institute North Indianapolis /ID# 264031	Carmel	Indiana	46290	Recruiting
Wolfe Eye Clinic - West Des Moines /ID# 263270	West Des Moines	Iowa	50266	Recruiting
The Retina Care Center /ID# 263263	Baltimore	Maryland	21209	Recruiting
Retina Specialist /ID# 264633	Towson	Maryland	21204	Recruiting
Associated Retinal Consultants /ID# 263289	Royal Oak	Michigan	48073	Recruiting
Retina Consultants of Minnesota (RCM) - Edina Retina Clinic /ID# 279427	Edina	Minnesota	55435	Recruiting
Mayo Clinic - Minnesota /ID# 263977	Rochester	Minnesota	55905	Recruiting
Retina Institute - St. Louis /ID# 263985	St Louis	Missouri	63128	Recruiting
Midwest Retina /ID# 263231	Dublin	Ohio	43016	Recruiting
Erie Retina Research /ID# 263287	Erie	Pennsylvania	16507	Recruiting
Charleston Neuroscience Institute /ID# 264037	Bluffton	South Carolina	29910	Recruiting
Charleston Neuroscience Institute /ID# 276425	Charleston	South Carolina	29414	Recruiting
Retina Consultants of South Carolina - Ladson /ID# 277596	Ladson	South Carolina	29456	Recruiting
Retina Consultants of America /ID# 264038	Mt. Pleasant	South Carolina	29464	Recruiting
Austin Retina Associates - Austin /ID# 266770	Austin	Texas	78705	Recruiting
Austin Clinical Research, LLC /ID# 263229	Austin	Texas	78750-2298	Recruiting
Star Retina /ID# 266386	Burleson	Texas	76028	Recruiting
Retina Consultants of Texas /ID# 263274	Houston	Texas	77056-3030	Recruiting
Retina Consultants of Texas - Westover /ID# 264209	San Antonio	Texas	78251	Recruiting
Rocky Mountain Retina Consultants /ID# 263266	Murray	Utah	84107	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07007065, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 13, 2026 · Synced Apr 29, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07007065 live on ClinicalTrials.gov.

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