A Research Study to Look at How Well CagriSema Helps People Living With Obesity Lose Weight and Maintain Weight Loss in the Long-term
Public ClinicalTrials.gov record NCT07011667. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Cagrilintide s.c. in Combination With Semaglutide s.c. (CagriSema s.c.) Once Weekly for Weight Management and Long-term Weight Maintenance in Participants With Obesity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will look at how well CagriSema helps people living with obesity to lose weight and maintain the weight loss long-term. The study has 2 parts: The first part is called 'the main study' and the second part is called 'the extension study'. In the main study participants will either get CagriSema (a study medicine) or placebo (a dummy medicine that looks like CagriSema but has no active ingredient). Which treatment participants get is decided by chance. Participants are two times more likely to get CagriSema than placebo. If participants get CagriSema in the main study, participants will continue on CagriSema in the extension study. Which dose of CagriSema participants will continue on is decided by chance. If participants get placebo in the main study, participants will get CagriSema in the extension study. Participants will take one injection of study medicine once a week. The study will last for about 3 years and 3 months.
Study identification
- NCT ID
- NCT07011667
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 609 participants
Conditions and interventions
Conditions
Interventions
- CagriSema (Cagrilintide B and Semaglutide I) Drug
- Placebo matched to CagriSema (Cagrilintide B and Semaglutide I) Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 3, 2025 (Actual)
- Primary completion
- Mar 1, 2027 (Estimated)
- Completion
- Oct 17, 2028 (Estimated)
- Last update posted
- Sep 30, 2026
2025 – 2028
United States locations
- U.S. sites
- 47
- U.S. states
- 19
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| FDRC | Costa Mesa | California | 92627 | — |
| Linda Vista Health Care Ctr | San Diego | California | 92111 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Jacksonville Ctr For Clin Res | Jacksonville | Florida | 32216 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| Florida Inst For Clin Res LLC | Orlando | Florida | 32825 | — |
| Oviedo Medical Research, LLC | Oviedo | Florida | 32765 | — |
| Center for Diab,Obes & Metab | Pembroke Pines | Florida | 33024 | — |
| Hope Clin Res & Wellness | Conyers | Georgia | 30094 | — |
| Endocrine Research Solutions | Roswell | Georgia | 30076 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Endeavor Health | Skokie | Illinois | 60077 | — |
| Evanston Premier Hlthcr Res | Skokie | Illinois | 60077 | — |
| Midwest Inst For Clin Res | Indianapolis | Indiana | 46260 | — |
| Iowa Diab & Endo Res Center | West Des Moines | Iowa | 50266 | — |
| Northern Pines Hlth Ctr, PC | Buckley | Michigan | 49620 | — |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | — |
| Amicis Centers of Clinical Research | St Louis | Missouri | 63128 | — |
| Mercury Str Med Grp, PLLC | Butte | Montana | 59701 | — |
| Southgate Medical Group, LLP | West Seneca | New York | 14224 | — |
| Great Lakes Medical Research | Westfield | New York | 14787 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27514 | — |
| Medication Mgmnt, LLC_Grnsboro | Greensboro | North Carolina | 27405 | — |
| PharmQuest Life Sciences LLC | Greensboro | North Carolina | 27408 | — |
| Accellacare_NC | Raleigh | North Carolina | 27609 | — |
| Piedmont Healthcare/Research | Statesville | North Carolina | 28625 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281-9236 | — |
| Lynn Institute of Norman | Norman | Oklahoma | 73072 | — |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | — |
| Coastal Carolina Res Ctr | North Charleston | South Carolina | 29405 | — |
| Hillcrest Clinical Research | Simpsonville | South Carolina | 29681-1538 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Amarillo Medical Specialists | Amarillo | Texas | 79124 | — |
| Velocity Clin Res, Dallas | Dallas | Texas | 75230 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Radiance Clinical Research | Lampasas | Texas | 76550 | — |
| DCOL Ctr for Clin Res | Longview | Texas | 75605 | — |
| Northeast Clinical Research of San Antonio | Schertz | Texas | 78154 | — |
| Consano Clinical Research, LLC | Shavano Park | Texas | 78231 | — |
| Washington Cntr Weight Mgmt | Arlington | Virginia | 22206 | — |
| Health Res of Hampton Roads | Newport News | Virginia | 23606 | — |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | — |
| Rainier Clin Res Ctr Inc | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07011667, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 30, 2026 · Synced Oct 24, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07011667 live on ClinicalTrials.gov.