Study of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
Public ClinicalTrials.gov record NCT07011719. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Active-Control, Multicenter Phase 3 Trial of Casdatifan and Cabozantinib Versus Placebo and Cabozantinib in Patients With Advanced Clear Cell Renal Cell Carcinoma
Study identification
- NCT ID
- NCT07011719
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Arcus Biosciences, Inc.
- Industry
- Enrollment
- 720 participants
Conditions and interventions
Interventions
- Cabozantinib Drug
- Casdatifan Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 7, 2025
- Primary completion
- Mar 31, 2028
- Completion
- Nov 30, 2030
- Last update posted
- Apr 27, 2026
2025 – 2030
United States locations
- U.S. sites
- 28
- U.S. states
- 19
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope - Phoenix Cancer Center | Goodyear | Arizona | 85338 | Recruiting |
| Mayo Clinic - Phoenix | Phoenix | Arizona | 85054 | Recruiting |
| City Of Hope National Medical Center | Duarte | California | 91010 | Recruiting |
| University of California San Diego Moores Cancer Center | La Jolla | California | 92103 | Recruiting |
| UCLA Hematology Oncology - 100 Med Plaza | Los Angeles | California | 90095 | Recruiting |
| University of California San Diego Moores Cancer Center | San Diego | California | 92103 | Recruiting |
| Yale University | New Haven | Connecticut | 06519 | Recruiting |
| Mayo Clinic in Florida | Jacksonville | Florida | 32224 | Recruiting |
| Piedmont Cancer Institute OneOncology | Atlanta | Georgia | 30318 | Recruiting |
| Emory University - Atlanta | Atlanta | Georgia | 30322 | Recruiting |
| City of Hope Cancer Center Atlanta | Newnan | Georgia | 30265 | Recruiting |
| City of Hope - Chicago Cancer Center | Zion | Illinois | 60099 | Recruiting |
| Indiana University Melvin and Bren Simon Cancer Center | Indianapolis | Indiana | 46202 | Recruiting |
| Norton Cancer Institute PARENT | Louisville | Kentucky | 40207 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Dana-Farber Cancer Institute | Boston | Massachusetts | 02215 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| The University of Nebraska Medical Center | Omaha | Nebraska | 68198 | Recruiting |
| University of Rochester Medical Center | Rochester | New York | 14642 | Recruiting |
| UNC Hospitals | Chapel Hill | North Carolina | 27514 | Recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44106 | Recruiting |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | Recruiting |
| Compass Oncology, OR | Portland | Oregon | 97212 | Recruiting |
| SCRI Oncology Partners | Nashville | Tennessee | 37203 | Recruiting |
| Vanderbilt | Nashville | Tennessee | 37232 | Recruiting |
| Texas Tech University Health Science Center | Lubbock | Texas | 79430 | Recruiting |
| The University of Utah - Huntsman Cancer Institute (HCI) | Salt Lake City | Utah | 84112 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 16 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07011719, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07011719 live on ClinicalTrials.gov.