A Clinical Trial to Evaluate Efficacy and Safety of Xeomin® Injections for Preventing Chronic Migraine
Public ClinicalTrials.gov record NCT07018713. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-blind, Placebo-controlled, Multicenter, Clinical Trial With Extension Period to Evaluate the Efficacy and Safety of Xeomin® Injections for the Prevention of Chronic Migraine
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
In this clinical trial, participants with chronic migraine will receive injections with Xeomin or Placebo into muscles of the head and neck. The purpose is to measure the change in monthly migraine days with Xeomin injections compared to Placebo injections. Trial details include: * Trial duration: 52 to 55 weeks; * Screening period: 4 to 5 weeks; * Treatment duration: 4 treatments, each about 12 weeks apart; and * Visit frequency: about every 4 weeks, 14 visits in total. The first and last visit and the 4 treatment visits are on-site, the other 8 visits are remote by phone / video call.
Study identification
- NCT ID
- NCT07018713
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 780 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 20, 2025
- Primary completion
- Sep 30, 2027
- Completion
- Feb 29, 2028
- Last update posted
- Sep 1, 2026
2025 – 2028
United States locations
- U.S. sites
- 48
- U.S. states
- 24
- U.S. cities
- 45
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TrialSphere Corp, Merz Investigational Site #0010513 | Chandler | Arizona | 85286 | Recruiting |
| Arizona Neuroscience Research, Merz Investigational Site #0010521 | Phoenix | Arizona | 85018 | Recruiting |
| Baptist Health Medical Center, Merz Investigational Site #0010520 | Little Rock | Arkansas | 72205 | Recruiting |
| Chemidox Clinical Trials Inc, Merz Investigational Site #0010488 | Lancaster | California | 93534 | Recruiting |
| Clinical Research Institute, Merz Investigational Site #0010487 | Los Angeles | California | 90048 | Recruiting |
| BNL Health, Merz Investigational Site #0010501 | Los Angeles | California | 90067 | Recruiting |
| Clinical Trials Management Services, Merz Investigational Site #0010526 | Thousand Oaks | California | 91360 | Recruiting |
| Hasbani Neurology, Merz Investigational Site #0010509 | New Haven | Connecticut | 06511 | Recruiting |
| Yale Center for Clinical Investigations, Merz Investigational Site #0010527 | New Haven | Connecticut | 06519 | Recruiting |
| New England Institute Neurology and Headache, Merz Investigational Site #0010441 | Stamford | Connecticut | 06905 | Recruiting |
| Northwest Florida Clinical Research Group, Merz Investigational Site #0010286 | Gulf Breeze | Florida | 32561 | Recruiting |
| Nexus Clinical Research Center, Merz Investigational Site #0010514 | Homestead | Florida | 33030 | Recruiting |
| Jacksonville Center for Clinical Research, Merz Investigational Site #0010515 | Jacksonville | Florida | 32216 | Recruiting |
| Clinical Research of Central Florida, Merz Investigational Site #0010532 | Lakeland | Florida | 33805 | Recruiting |
| University of Miami Miller School of Medicine, Merz Investigational Site #0010493 | Miami | Florida | 33136 | Recruiting |
| American Research Institute, Merz Investigational Site #0010492 | Miami | Florida | 33157 | Recruiting |
| Premiere Research Institute at Palm Beach Neurology, Merz Investigational Site #0010499 | West Palm Beach | Florida | 33407 | Recruiting |
| Accel Research - NeuroStudies, Merz Investigational Site #0010523 | Decatur | Georgia | 30030 | Recruiting |
| Hawaii Pacific Neuroscience, Merz Investigational Site #0010510 | Honolulu | Hawaii | 96817 | Recruiting |
| Kansas Institute of Research,, Merz Investigational Site #0010495 | Overland Park | Kansas | 66211 | Recruiting |
| Crescent City Headache and Neurology Center, Merz Investigational Site #0010517 | Chalmette | Louisiana | 70043 | Recruiting |
| DelRicht Clinical Research, Merz Investigational Site #0010518 | New Orleans | Louisiana | 70115 | Recruiting |
| Sinai Hospital of Baltimore, Merz Investigational Site #0010505 | Baltimore | Maryland | 21215 | Recruiting |
| MedVadis Research, Merz Investigational Site #0010524 | Waltham | Massachusetts | 02451 | Recruiting |
| Mass Institute of Clinical Research, Merz Investigational Site #0010506 | Westborough | Massachusetts | 01581 | Recruiting |
| Vida Clinical Studies, Merz Investigational Site #0010498 | Dearborn Heights | Michigan | 48127 | Recruiting |
| Quest Research Institute, Merz Investigational Site #0010484 | Farmington Hills | Michigan | 48334 | Recruiting |
| Mayo Clinic, Merz Investigational Site #0010212 | Rochester | Minnesota | 59505 | Recruiting |
| StudyMetrix Research, Merz Investigational Site #0010530 | City of Saint Peters | Missouri | 63303 | Recruiting |
| Quality Clinical Research, Merz Investigational Site #0010522 | Omaha | Nebraska | 68114 | Recruiting |
| Dent Neurosciences Research Center, Merz Investigational Site #0010486 | Amherst | New York | 14226 | Recruiting |
| Integrative Clinical Trials, Merz Investigational Site #0010496 | Brooklyn | New York | 11229 | Recruiting |
| New York Neurology Associates, Merz Investigational Site #0010500 | New York | New York | 10003 | Recruiting |
| True North Neurology, Merz Investigational Site #0010508 | Port Jefferson Station | New York | 11776 | Recruiting |
| Rochester Clinical Research, Merz Investigational Site #0010512 | Rochester | New York | 14609 | Recruiting |
| Upstate Clinical Research Associates, Merz Investigational Site #0010485 | Williamsville | New York | 14221 | Recruiting |
| Dayton Center for Neurological Disorders, Merz Investigational Site #0010531 | Centerville | Ohio | 45459 | Recruiting |
| Headache Center of Hope, Merz Investigational Site #0010528 | Cincinnati | Ohio | 45236 | Recruiting |
| University Hospitals Cleveland Medical Center, Merz Investigational Site #0010491 | Cleveland | Ohio | 44106 | Recruiting |
| Tekton Research, Merz Investigational Site #0010494 | Edmond | Oklahoma | 73013 | Recruiting |
| Thomas Jefferson University, Merz Investigational Site #0010354 | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Coastal Neurology, Merz Investigational Site #0010503 | Port Royal | South Carolina | 29935 | Recruiting |
| Alina Clinical Trials, Merz Investigational Site #0010511 | Dallas | Texas | 75209 | Recruiting |
| Lone Star Neurology, Merz Investigational Site #0010497 | Frisco | Texas | 75035 | Recruiting |
| MedStar Health - Department of Neurology, Merz Investigational Site #0010231 | McLean | Virginia | 22101 | Recruiting |
| Gershon Pain Specialists, Merz Investigational Site #0010519 | Virginia Beach | Virginia | 23454 | Recruiting |
| EvergreenHealth Research Department, Merz Investigational Site #0010516 | Kirkland | Washington | 98034 | Recruiting |
| Gundersen Health System, Merz Investigational Site #0010507 | La Crosse | Wisconsin | 54601 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 63 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07018713, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 1, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07018713 live on ClinicalTrials.gov.