A Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression

ClinicalTrials.gov ID: NCT07023627

Public ClinicalTrials.gov record NCT07023627. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Oct 8, 2026, 10:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Single-Arm Study of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer With Cyclin E1 Overexpression (MAESTRA 1)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This study will evaluate the safety and efficacy of INCB123667 in Participants With Platinum-Resistant Ovarian Cancer (PROC) With Cyclin E1 Overexpression.

Study identification

NCT ID: NCT07023627
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Incyte Corporation; Industry
Enrollment: 160 participants

Conditions and interventions

Conditions

Ovarian Cancer

Interventions

INCB123667 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 99 Years
Sex: Female
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Nov 12, 2025 (Actual)
Primary completion: Apr 27, 2027 (Estimated)
Completion: Oct 24, 2027 (Estimated)
Last update posted: Sep 15, 2026

2025 – 2027

United States locations

U.S. sites: 38
U.S. states: 27
U.S. cities: 38

Facility	City	State	ZIP	Site status
Usa Health Mitchell Cancer Institute	Mobile	Alabama	36604	Recruiting
University of California, Los Angeles Medical Center	Los Angeles	California	90024-6995	Recruiting
Scripps Healthscripps Mercy Hospital Prebys Cancer Center	San Diego	California	92103	Recruiting
Medstar Georgetown University Hospital	Washington D.C.	District of Columbia	20010	Recruiting
Florida Cancer Specialists & Research Institute	Fort Myers	Florida	33901	Recruiting
Sylvester Comprehensive Cancer Center	Miami	Florida	33136	Recruiting
Mount Sinai Comprehensive Cancer Center	Miami Beach	Florida	33140	Recruiting
Florida Cancer Specialists & Research Institute	West Palm Beach	Florida	33401	Recruiting
Northeast Georgia Medical Center Gainesville	Gainesville	Georgia	30501	Recruiting
Parkview Research Center	Fort Wayne	Indiana	46845	Recruiting
University of Iowa Hospital and Clinics	Iowa City	Iowa	52242-1009	Recruiting
Norton Cancer Institute	Louisville	Kentucky	40207	Recruiting
Trials365, Llc	Shreveport	Louisiana	71103	Recruiting
Greater Baltimore Medical Center	Baltimore	Maryland	21204	Recruiting
Massachusetts General Hospital	Boston	Massachusetts	02114	Recruiting
Umass Memorial Medical Center, Inc.	Worcester	Massachusetts	01605	Recruiting
University of Michigan Health System	Ann Arbor	Michigan	48109	Recruiting
Minnesota Oncology-Minneapolis	Minneapolis	Minnesota	55404	Recruiting
University of Mississippi Medical Center	Jackson	Mississippi	39216	Recruiting
Washington University	St Louis	Missouri	63110	Recruiting
St. Vincent Regional Hospital - West End Clinic	Billings	Montana	59106	Recruiting
Nebraska Methodist Hospital	Omaha	Nebraska	68114	Recruiting
John Theurer Cancer Center, Hackensack University Medical Center	Hackensack	New Jersey	07601	Recruiting
Laura and Isaac Perlmutter Cancer Center	New York	New York	10016	Recruiting
State University of New York Upstate Medical Unive	Syracuse	New York	13210	Recruiting
Oncology Hematology Care, Inc	Cincinnati	Ohio	45242	Recruiting
The Mark H Zangmeister Cancer Center Ohio	Columbus	Ohio	43219	Recruiting
The Ohio State University Wexner Medical Center Division of Gynecologic Oncology	Hilliard	Ohio	43026	Recruiting
Penn State College of Medicine	Hershey	Pennsylvania	17033	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
Texas Oncology-Austin Center	Austin	Texas	78731	Recruiting
Texas Oncology-San Antonio Medical Center Pharmacy	San Antonio	Texas	78229	Recruiting
Texas Oncology-Tyler	Tyler	Texas	75702	Recruiting
Utah Cancer Specialists	Salt Lake City	Utah	84106	Recruiting
Virginia Cancer Specialists	Fairfax	Virginia	22031	Recruiting
Carilion Clinic	Roanoke	Virginia	24016-4962	Recruiting
West Virginia University	Morgantown	West Virginia	26506	Recruiting
Froedtert & the Medical College of Wisconsin	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07023627, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Sep 15, 2026 · Synced Oct 8, 2026

Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07023627 live on ClinicalTrials.gov.

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