Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

ClinicalTrials.gov ID: NCT07028749

Public ClinicalTrials.gov record NCT07028749. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Sep 2, 2026, 6:26 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2b Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Study of MAR001 in Patients With Elevated Triglycerides and Remnant Cholesterol (TYDAL-TIMI 78)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The primary objective of the study is to evaluate the effect of MAR001 compared to placebo on levels of TG in adults with elevated TG and RC.

Study identification

NCT ID: NCT07028749
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Marea Therapeutics; Industry
Enrollment: 316 participants

Conditions and interventions

Conditions

Hypertriglyceridemia

Interventions

MAR001 Drug
Placebo Drug

Drug

Eligibility (public fields only)

Age range: 18 Years to 75 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jun 29, 2025
Primary completion: Oct 31, 2027
Completion: Mar 31, 2028
Last update posted: Aug 4, 2026

2025 – 2028

United States locations

U.S. sites: 26
U.S. states: 16
U.S. cities: 26

Facility	City	State	ZIP	Site status
Marea Site 328	Anniston	Alabama	36207	Recruiting
Marea Site 329	Mobile	Alabama	36608	Recruiting
Marea Site 313	Little Rock	Arkansas	72204	Recruiting
Marea Site 306	Hamden	Connecticut	06517	Recruiting
Marea Site 302	Boca Raton	Florida	33434	Recruiting
Marea Site 307	Port Saint Lucie	Florida	34952	Recruiting
Marea Site 310	Columbus	Georgia	31904	Recruiting
Marea Site 319	Peachtree Corners	Georgia	30092	Recruiting
Marea Site 317	Park Ridge	Illinois	60068	Recruiting
Marea Site 325	Springfield	Illinois	62702	Recruiting
Marea Site 301	Louisville	Kentucky	40213	Recruiting
Marea Site 316	Baltimore	Maryland	21229	Recruiting
Marea Site 330	Kansas City	Missouri	64151	Recruiting
Marea Site 305	St Louis	Missouri	63110	Recruiting
Marea Site 304	Great Neck	New York	11021	Recruiting
Marea Site 318	New Windsor	New York	12553	Recruiting
Marea Site 303	Greensboro	North Carolina	27405	Recruiting
Marea Site 315	Winston-Salem	North Carolina	27104	Recruiting
Marea Site 314	Greenville	South Carolina	29607	Recruiting
Marea Site 320	Little River	South Carolina	29566	Recruiting
Marea Site 326	Memphis	Tennessee	38119	Recruiting
Marea Site 322	Amarillo	Texas	79124	Recruiting
Marea Site 308	McKinney	Texas	75071	Recruiting
Marea Site 312	San Antonio	Texas	78229	Recruiting
Marea Site 321	Manassas	Virginia	20109	Recruiting
Marea Site 309	Tacoma	Washington	98405	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 28 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07028749, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Aug 4, 2026 · Synced Sep 2, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07028749 live on ClinicalTrials.gov.

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