A Study to Learn About Medicine Called Ritlecitinib in Children Aged Between 6 to 12 Years With Severe Alopecia Areata
Public ClinicalTrials.gov record NCT07029711. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A PHASE 3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF RITLECITINIB IN PEDIATRIC PARTICIPANTS 6 TO LESS THAN 12 YEARS OF AGE WITH SEVERE ALOPECIA AREATA
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn about the safety and effects of the study medicine (called ritlecitinib) for the possible treatment of severe alopecia areata. Alopecia areata is a condition that causes hair loss. This study is seeking participants who have: * at least 50% scalp hair loss due to alopecia areata. * received varicella vaccination (2 doses) or have been infected by varicella zoster virus before based on blood test reports. * history of clinical response failure to alopecia areata treatment (for children in EU/UK only). All participants in this study will receive either study medicine (ritlecitinib) or placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. One-third of participants will receive ritlecitinib higher dose, one-third participants will receive ritlecitinib lower dose, and one-third participants will receive placebo. The study medicine is a capsule that is taken by mouth. It is taken once each day at home. The study will compare the experiences of participants receiving ritlecitinib to participants receiving placebo. This will help see if ritlecitinib is safe and effective. Participants will take part in this study for 6 months. During this time, they will have 8 study visits at the study clinic. The study team will also call participants about 8 times over the phone.
Study identification
- NCT ID
- NCT07029711
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 208 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 6 Years to 11 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 30, 2025
- Primary completion
- Dec 1, 2026
- Completion
- Jan 5, 2027
- Last update posted
- Aug 25, 2026
2025 – 2027
United States locations
- U.S. sites
- 31
- U.S. states
- 15
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UCI Dermatology Clinical Research | Irvine | California | 92697 | — |
| Southern California Clinical Research | Santa Ana | California | 92701 | — |
| Children's Hospital Colorado | Aurora | Colorado | 80045 | — |
| Children's National Medical Center | Washington D.C. | District of Columbia | 20010 | — |
| Pediatric Skin Research | Miami | Florida | 33156 | — |
| Endeavor Health Audiology -CHICAGO | Chicago | Illinois | 60625 | — |
| Endeavor Health Behavioral Health - Evanston | Evanston | Illinois | 60201 | — |
| Endeavor Health Clinical Operations | Evanston | Illinois | 60201 | — |
| Endeavor Health Audiology -LAKE BLUFF | Lake Bluff | Illinois | 60044 | — |
| Endeavor Health Audiology-NORTHBROOK | Northbrook | Illinois | 60062 | — |
| Endeavor Health Audiology-SKOKIE | Skokie | Illinois | 60076 | — |
| Endeavor Health Clinical Operations | Skokie | Illinois | 60077 | — |
| Endeavor Health Lab Services - Old Orchard | Skokie | Illinois | 60077 | — |
| Dawes Fretzin Clinical Research Group, LLC | Indianapolis | Indiana | 46250 | — |
| Kindred Hair and Skin Center | Marriottsville | Maryland | 21104 | — |
| Michigan Dermatology Institute | Waterford | Michigan | 48328 | — |
| Ear, Nose and Throat Consultants, LLC | Omaha | Nebraska | 68144 | — |
| Skin Specialists, PC dba Schlessinger MD | Omaha | Nebraska | 68144 | — |
| Complete Behavior Health (Dr. Brittany Marshall, Licensed Psychologist) | Papillion | Nebraska | 68046 | — |
| University of New Mexico Health Sciences Center | Albuquerque | New Mexico | 87102 | — |
| University of New Mexico-IDS Pharmacy | Albuquerque | New Mexico | 87106 | — |
| Northwest Dermatology Institute | Portland | Oregon | 97210 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Medical University of South Carolina Department of Dermatology and Dermatologic Surgery | Charleston | South Carolina | 29425 | — |
| Dell Children's Medical Center | Austin | Texas | 78723 | — |
| Driscoll Children's Hospital | Corpus Christi | Texas | 78411 | — |
| 3A Research - West Location | El Paso | Texas | 79902 | — |
| Austin Institute for Clinical Research | Pflugerville | Texas | 78660 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Children's Wisconsin | Milwaukee | Wisconsin | 53226 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07029711, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 25, 2026 · Synced Sep 9, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07029711 live on ClinicalTrials.gov.