A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Public ClinicalTrials.gov record NCT07033494. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study to Evaluate the Efficacy and Safety of MK-2214 in Participants With Early Alzheimer's Disease
Study identification
- NCT ID
- NCT07033494
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Merck Sharp & Dohme LLC
- Industry
- Enrollment
- 340 participants
Conditions and interventions
Conditions
Interventions
- MK-2214 Biological
- Placebo Drug
Biological · Drug
Eligibility (public fields only)
- Age range
- 50 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 15, 2025
- Primary completion
- Apr 29, 2029
- Completion
- Apr 29, 2029
- Last update posted
- May 6, 2026
2025 – 2029
United States locations
- U.S. sites
- 36
- U.S. states
- 13
- U.S. cities
- 35
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Irvine Clinical Research ( Site 1041) | Irvine | California | 92614 | Recruiting |
| Healthy Brain Clinic ( Site 1005) | Long Beach | California | 90804 | Recruiting |
| Inglewood Clinical ( Site 1062) | Los Angeles | California | 90056 | Recruiting |
| Anderson Clinical Research ( Site 1024) | Redlands | California | 92374 | Recruiting |
| UCSF Memory and Aging Center ( Site 1031) | San Francisco | California | 94158 | Recruiting |
| Syrentis Clinical Research ( Site 1001) | Santa Ana | California | 92705 | Recruiting |
| Yale University, Alzheimer's Disease Research Unit ( Site 1059) | New Haven | Connecticut | 06510 | Recruiting |
| JEM Research Institute ( Site 1046) | Atlantis | Florida | 33462 | Recruiting |
| Neuropsychiatric Research Center of Southwest Florida ( Site 1003) | Fort Myers | Florida | 33912 | Recruiting |
| Indago Research & Health Center, Inc ( Site 1044) | Hialeah | Florida | 33012 | Recruiting |
| K2 Medical Research ( Site 1047) | Maitland | Florida | 32750 | Recruiting |
| ClinCloud LLC ( Site 1039) | Melbourne | Florida | 32940 | Recruiting |
| Aqualane Clinical Research ( Site 1035) | Naples | Florida | 34105 | Recruiting |
| Suncoast Clinical Research ( Site 1007) | New Port Richey | Florida | 34652 | Recruiting |
| Renstar Medical Research ( Site 1012) | Ocala | Florida | 34471 | Recruiting |
| Charter Research - Orlando ( Site 1051) | Orlando | Florida | 32803 | Recruiting |
| Axiom Brain Health ( Site 1029) | Tampa | Florida | 33609 | Recruiting |
| K2 Medical Research ( Site 1020) | Tampa | Florida | 33634 | Recruiting |
| Charter Research - Lady Lake ( Site 1019) | The Villages | Florida | 32162 | Recruiting |
| Conquest Research LLC ( Site 1053) | Winter Park | Florida | 32789 | Recruiting |
| CenExel iResearch, LLC ( Site 1015) | Decatur | Georgia | 30030 | Recruiting |
| Alexian Brothers Medical Center-Neurosciences ( Site 1017) | Elk Grove Village | Illinois | 60007 | Recruiting |
| Boston Center for Memory ( Site 1008) | Newton | Massachusetts | 02459 | Recruiting |
| Clinical Research Professionals ( Site 1004) | Chesterfield | Missouri | 63005 | Recruiting |
| The Cognitive and Research Center of New Jersey - Ridgewood ( Site 1064) | Ridgewood | New Jersey | 07450 | Recruiting |
| The Cognitive and Research Center of NJ ( Site 1057) | Springfield | New Jersey | 07081 | Recruiting |
| CenExel- AMRI ( Site 1018) | Toms River | New Jersey | 08755 | Recruiting |
| Alzheimer Disease Research Center (ADRC) ( Site 1000) | Albany | New York | 12208 | Recruiting |
| Mid Hudson Medical Research ( Site 1050) | New Windsor | New York | 12553 | Recruiting |
| Basil Clinical ( Site 1065) | Queens | New York | 11413 | Recruiting |
| AMC Research, LLC ( Site 1006) | Matthews | North Carolina | 28105 | Recruiting |
| Insight Clinical Trials ( Site 1011) | Independence | Ohio | 44131 | Recruiting |
| Neuro-Behavioral Clinical Research ( Site 1028) | North Canton | Ohio | 44720 | Recruiting |
| Flourish Research ( Site 1048) | Plymouth Meeting | Pennsylvania | 19462 | Recruiting |
| Gadolin Research ( Site 1032) | Beaumont | Texas | 77702 | Recruiting |
| Horizon Clinical Research Center - Houston ( Site 1026) | Cypress | Texas | 77429 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07033494, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 10, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07033494 live on ClinicalTrials.gov.