AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001)
Public ClinicalTrials.gov record NCT07038343. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Antitumor Activity of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors
Study identification
- NCT ID
- NCT07038343
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Lead sponsor
- Avenzo Therapeutics, Inc.
- Industry
- Enrollment
- 430 participants
Conditions and interventions
Conditions
Interventions
- AVZO-1418 Drug
- Combination Agent 1 Drug
- Combination Agent 2 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Not listed
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 3, 2025
- Primary completion
- May 31, 2030
- Completion
- Nov 30, 2030
- Last update posted
- Feb 19, 2026
2025 – 2030
United States locations
- U.S. sites
- 16
- U.S. states
- 13
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Avenzo Therapeutics Recruiting Site | Gilbert | Arizona | 85234 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Los Angeles | California | 90048 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Denver | Colorado | 80218 | Recruiting |
| Avenzo Therapeutics Recruiting Site | New Haven | Connecticut | 06510 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Washington D.C. | District of Columbia | 20007 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Orlando | Florida | 32827 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Sarasota | Florida | 34232 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Atlanta | Georgia | 30322 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Boston | Massachusetts | 02215 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Dallas | Texas | 75039 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Houston | Texas | 77054 | Recruiting |
| Avenzo Therapeutics Recruiting Site | San Antonio | Texas | 78229 | Recruiting |
| Avenzo Therapeutics Recruiting Site | West Valley City | Utah | 84119 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Fairfax | Virginia | 22031 | Recruiting |
| Avenzo Therapeutics Recruiting Site | Seattle | Washington | 98109 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07038343, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 19, 2026 · Synced Apr 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07038343 live on ClinicalTrials.gov.