Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Bipolar I Disorder
Public ClinicalTrials.gov record NCT07046494. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of RAP-219 for the Acute Treatment of Manic Episodes, With or Without Mixed Features, Associated With Bipolar I Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a clinical research study for an investigational drug called RAP-219 in participants with bipolar I disorder. This study is being conducted to determine if RAP-219 is safe and effective in participants experiencing mania associated with bipolar I disorder.
Study identification
- NCT ID
- NCT07046494
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 253 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 25, 2025 (Actual)
- Primary completion
- Aug 5, 2026 (Actual)
- Completion
- Oct 2026 (Estimated)
- Last update posted
- Aug 10, 2026
2025 – 2026
United States locations
- U.S. sites
- 20
- U.S. states
- 10
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pillar Clinical Research - Little Rock | Little Rock | Arkansas | 72204 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| Inland Psychiatric Medical Group - Chino | Chino | California | 91710 | — |
| Synergy Clinical Research Center - San Diego | Lemon Grove | California | 91945 | — |
| Collaborative Neuroscience Research - Los Alamitos | Los Alamitos | California | 90720 | — |
| NRC Research Institute - Orange | Orange | California | 92868 | — |
| NeuroBehavioral Hospitals of the Palm Beaches - South | Boynton Beach | Florida | 33426 | — |
| United Research Institute | Hialeah | Florida | 33012 | — |
| CenExel - Hollywood | Hollywood | Florida | 33024 | — |
| Segal Trials - Miami Lakes Medical Research Early Phase, Inpatient & Outpatient Site | Miami Lakes | Florida | 33016 | — |
| Neuroscience Research Institute at Ambrosia | West Palm Beach | Florida | 33407 | — |
| CenExel - Decatur | Decatur | Georgia | 30030 | — |
| Pillar Clinical Research - Chicago | Chicago | Illinois | 60641 | — |
| CenExel - Gaithersburg | Gaithersburg | Maryland | 20877 | — |
| Arch Clinical Trials | St Louis | Missouri | 63125 | — |
| Richmond Behavioral Associates | Staten Island | New York | 10314 | — |
| New Hope Clinical Research | Charlotte | North Carolina | 28211 | — |
| Community Clinical Research, Inc. | Austin | Texas | 78754 | — |
| HD Research - Memorial Hermann Village | Houston | Texas | 77043 | — |
| Pillar Clinical Research - Richardson | Richardson | Texas | 75080 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07046494, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 10, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07046494 live on ClinicalTrials.gov.