Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD
Public ClinicalTrials.gov record NCT07051707. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Multicenter, Randomized, Study to Evaluate Safety and Efficacy After Treatment With the dNerva Lung Denervation System in Subjects With Chronic Obstructive Pulmonary Disease (COPD) (AIRFLOW-4)
Study identification
- NCT ID
- NCT07051707
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Lead sponsor
- Nuvaira, Inc.
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- Targeted Lung Denervation (TLD) Device
Device
Eligibility (public fields only)
- Age range
- 40 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Feb 23, 2026
- Primary completion
- Apr 29, 2028
- Completion
- Oct 30, 2029
- Last update posted
- Apr 27, 2026
2026 – 2029
United States locations
- U.S. sites
- 10
- U.S. states
- 8
- U.S. cities
- 10
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama-Birmingham Hospital - UAB Lung Health Center | Birmingham | Alabama | 35233 | Recruiting |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | Recruiting |
| Henry Ford Hospital - Lung and Pulmonary Care | Detroit | Michigan | 48202 | Recruiting |
| Wake Forest School of Medicine | Salem | North Carolina | 27104 | Not yet recruiting |
| Ohio State University Medical Center - Ohio State Lung Center | Columbus | Ohio | 43210 | Recruiting |
| Penn Highlands - Lung Innovations/Clinical Research Associates | DuBois | Pennsylvania | 15801 | Recruiting |
| Temple University - Temple Lung Center | Philadelphia | Pennsylvania | 19140 | Recruiting |
| University of Pittsburgh Medical Center - UMPC Comprehensive Lung Center | Pittsburgh | Pennsylvania | 15213 | Not yet recruiting |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298 | Not yet recruiting |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07051707, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced Apr 29, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07051707 live on ClinicalTrials.gov.