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Recruiting Phase 3 Interventional

TRITON-CM: A Study to Evaluate Nucresiran in Patients With Transthyretin Amyloidosis With Cardiomyopathy

ClinicalTrials.gov ID: NCT07052903

Public ClinicalTrials.gov record NCT07052903. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 5, 2026, 8:05 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

TRITON-CM: A Phase 3 Global, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Transthyretin-Mediated Amyloidosis With Cardiomyopathy (ATTR Amyloidosis With Cardiomyopathy)

Study identification

NCT ID
NCT07052903
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Alnylam Pharmaceuticals
Industry
Enrollment
1,250 participants

Conditions and interventions

Interventions

  • Nucresiran Drug
  • Sterile Normal Saline (0.9% NaCl) Drug

Drug

Eligibility (public fields only)

Age range
18 Years to 85 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 1, 2025
Primary completion
May 27, 2030
Completion
Nov 29, 2032
Last update posted
Apr 16, 2026

2025 – 2032

United States locations

U.S. sites
34
U.S. states
20
U.S. cities
30
Facility City State ZIP Site status
Clinical Trial Site La Jolla California 92037 Recruiting
Clinical Trial Site Stanford California 94305 Recruiting
Clinical Trial Site Norwich Connecticut 06360 Recruiting
Clinical Trial Site Washington D.C. District of Columbia 20010 Recruiting
Clinical Trial Site Brandon Florida 33511 Recruiting
Clinical Trial Site Miami Florida 33125 Recruiting
Clinical Trial Site Atlanta Georgia 30309 Recruiting
Clinical Trial Site Gainesville Georgia 30501 Recruiting
Clinical Trial Site Tucker Georgia 30084 Recruiting
Clinical Trial Site Indianapolis Indiana 46202 Recruiting
Clinical Trial Site Indianapolis Indiana 46260 Recruiting
Clinical Trial Site Kansas City Kansas 66160 Recruiting
Clinical Trial Site Baltimore Maryland 21287 Recruiting
Clinical Trial Site Boston Massachusetts 02115 Recruiting
Clinical Trial Site Boston Massachusetts 02118 Recruiting
Clinical Trial Site Detroit Michigan 48202 Recruiting
Clinical Trial Site Rochester Minnesota 55905 Recruiting
Clinical Trial Site St Louis Missouri 63110 Recruiting
Clinical Trial Site Manhasset New York 11030 Recruiting
Clinical Trial Site New York New York 10029 Recruiting
Clinical Trial Site New York New York 10032 Recruiting
Clinical Trial Site New York New York 10065 Recruiting
Clinical Trial Site The Bronx New York 10467 Recruiting
Clinical Trial Site Charlotte North Carolina 28204 Recruiting
Clinical Trial Site Cleveland Ohio 44195 Recruiting
Clinical Trial Site Lancaster Pennsylvania 17602 Recruiting
Clinical Trial Site Philadelphia Pennsylvania 19104 Recruiting
Clinical Trial Site Dallas Texas 75246 Recruiting
Clinical Trial Site Houston Texas 77030 Recruiting
Clinical Trial Site Plano Texas 75024 Recruiting
Clinical Trial Site Salt Lake City Utah 84132 Recruiting
Clinical Trial Site Charlottesville Virginia 22903 Recruiting
Clinical Trial Site Norfolk Virginia 23507 Recruiting
Clinical Trial Site Spokane Washington 99204 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 173 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07052903, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07052903 live on ClinicalTrials.gov.

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