Obe-cel in Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

ClinicalTrials.gov ID: NCT07053800

Public ClinicalTrials.gov record NCT07053800. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced Apr 28, 2026, 3:52 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Single-Arm, Open-Label, Phase II Study to Determine the Safety and Efficacy of Obecabtagene Autoleucel (Obe-cel) in Participants With Severe, Refractory Systemic Lupus Erythematosus With Active Lupus Nephritis

Study identification

NCT ID: NCT07053800
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Autolus Limited; Industry
Enrollment: 35 participants

Conditions and interventions

Conditions

Lupus Nephritis

Interventions

Obecabtagene autoleucel Biological

Biological

Eligibility (public fields only)

Age range: 12 Years to 65 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 15, 2026
Primary completion: Jul 31, 2028
Completion: Sep 30, 2029
Last update posted: Apr 26, 2026

2026 – 2029

United States locations

U.S. sites: 11
U.S. states: 6
U.S. cities: 9

Facility	City	State	ZIP	Site status
Banner MD Anderson Cancer Center at Canyon Springs	Gilbert	Arizona	85234	Active, not recruiting
City of Hope	Duarte	California	91010	Active, not recruiting
Stanford University	Stanford	California	94305	Active, not recruiting
Tampa General Hospital	Tampa	Florida	33606	Active, not recruiting
H Lee Moffitt Cancer Center and Research Institute	Tampa	Florida	33612	Active, not recruiting
Emory	Atlanta	Georgia	30322	Active, not recruiting
The Tisch Cancer Institute - 1470 Madison Avenue	New York	New York	10029	Active, not recruiting
State University of New York Upstate Medical Center (SUNY)	Syracuse	New York	13210	Active, not recruiting
Texas Childrens Hospital/Baylor	Houston	Texas	77030	Active, not recruiting
Accurate Clinical Research Inc - Victoria	Houston	Texas	77034	Active, not recruiting
Texas Transplant Institute	San Antonio	Texas	78229	Active, not recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07053800, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 26, 2026 · Synced Apr 28, 2026

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The complete protocol, eligibility criteria, and contact information for NCT07053800 live on ClinicalTrials.gov.

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