A Study to Compare the Combination of BMS-986504 With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

ClinicalTrials.gov ID: NCT07063745

Public ClinicalTrials.gov record NCT07063745. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 8, 2026, 5:02 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized Phase 2/3 Study of BMS-986504 in Combination With Pembrolizumab and Chemotherapy Versus Placebo Plus Pembrolizumab and Chemotherapy in First-line Metastatic Non-small Cell Lung Cancer Participants With Homozygous MTAP Deletion

Study identification

NCT ID: NCT07063745
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2, Phase 3
Lead sponsor: Bristol-Myers Squibb; Industry
Enrollment: 590 participants

Conditions and interventions

Conditions

Metastatic Non-small Cell Lung Cancer With MTAP Deletion

Interventions

BMS-986504 Drug
Carboplatin Drug
Cisplatin Drug
Nab-paclitaxel Drug
Paclitaxel Drug
Pembrolizumab Drug
Pemetrexed Drug
Placebo Other

Drug · Other

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jan 1, 2026
Primary completion: Aug 11, 2031
Completion: Aug 11, 2031
Last update posted: May 5, 2026

2026 – 2031

United States locations

U.S. sites: 42
U.S. states: 25
U.S. cities: 39

Facility	City	State	ZIP	Site status
Alaska Oncology and Hematology	Anchorage	Alaska	99508	Recruiting
Mayo Clinic in Arizona - Phoenix	Phoenix	Arizona	85054	Recruiting
Local Institution - 0120	Tucson	Arizona	85724	Not yet recruiting
Highlands Oncology Group	Springdale	Arkansas	72762	Recruiting
Local Institution - 0497	Los Alamitos	California	90720	Not yet recruiting
USC/Norris Comprehensive Cancer Center	Los Angeles	California	90033	Recruiting
Local Institution - 0444	Los Angeles	California	90067	Withdrawn
Local Institution - 0606	Newark	Delaware	19713	Not yet recruiting
Local Institution - 0152	Fort Lauderdale	Florida	33316	Not yet recruiting
Mayo Clinic in Florida	Jacksonville	Florida	32224	Recruiting
Local Institution - 0430	St. Petersburg	Florida	33709	Withdrawn
St. Luke's Cancer Institute: Boise	Boise	Idaho	83712	Recruiting
Local Institution - 0605	Decatur	Illinois	62526	Not yet recruiting
Baptist Health Lexington	Lexington	Kentucky	40503	Recruiting
University of Kentucky Chandler Medical Center	Lexington	Kentucky	40536	Recruiting
Local Institution - 0127	Scarborough	Maine	04074	Not yet recruiting
Dana-Farber Cancer Institute	Boston	Massachusetts	02215	Recruiting
Local Institution - 0418	Ann Arbor	Michigan	48109	Not yet recruiting
Local Institution - 0405	Detroit	Michigan	48201	Not yet recruiting
Local Institution - 0420	Traverse City	Michigan	49684	Not yet recruiting
Mayo Clinic in Rochester, Minnesota	Rochester	Minnesota	55905	Recruiting
Oncology Hematology West P.C. dba Nebraska Cancer Specialists	Omaha	Nebraska	68130	Recruiting
Local Institution - 0467	Lebanon	New Hampshire	03756	Not yet recruiting
Local Institution - 0600	Manchester	New Hampshire	03103	Not yet recruiting
WMCHealth Advanced Physician Services	Hawthorne	New York	10532	Recruiting
Local Institution - 0128	Rochester	New York	14642	Not yet recruiting
Local Institution - 0518	Schenectady	New York	12308	Not yet recruiting
Local Institution - 0514	Winston-Salem	North Carolina	27157	Not yet recruiting
Local Institution - 0163	Cleveland	Ohio	44195	Not yet recruiting
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive Cancer Center	Columbus	Ohio	43210	Recruiting
Providence Portland Medical Center	Portland	Oregon	97213	Recruiting
Kaiser Permanente Interstate Medical Office Central	Portland	Oregon	97227	Recruiting
Local Institution - 0608	Greenville	South Carolina	29607	Not yet recruiting
Local Institution - 0515	Knoxville	Tennessee	37920	Not yet recruiting
Local Institution - 0433	Dallas	Texas	75390	Not yet recruiting
Renovatio Clinical - El Paso	El Paso	Texas	79915	Recruiting
University of Texas MD Anderson Cancer Center	Houston	Texas	77030	Recruiting
Local Institution - 0377	The Woodlands	Texas	77380	Withdrawn
Huntsman Cancer Institute	Salt Lake City	Utah	84112	Recruiting
Local Institution - 0131	Fairfax	Virginia	22031	Withdrawn
Local Institution - 0186	Richmond	Virginia	23298	Not yet recruiting
Fred Hutchinson Cancer Center	Seattle	Washington	98109	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 234 non-U.S. sites.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT07063745, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted May 5, 2026 · Synced May 8, 2026

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07063745 live on ClinicalTrials.gov.

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