ClinicalTrials.gov record
Single Intravitreal (IVT) Injection of 4D-150 in Patients With Macular Neovascularization Secondary to Age-Related Macular Degeneration
ClinicalTrials.gov ID: NCT07064759
Public ClinicalTrials.gov record NCT07064759. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 20, 2026, 12:57 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Double-Masked, Active-Controlled Trial of a Single Intravitreal Injection of 4D-150 in Adults With Macular Neovascularization Secondary to Age-Related Macular Degeneration
Study identification
- NCT ID
- NCT07064759
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- 4D Molecular Therapeutics
- Industry
- Enrollment
- 480 participants
Conditions and interventions
Interventions
- 4D-150 IVT (3E10 vg/eye) Biological
- EYLEA® (aflibercept) Injection 2 mg (0.05mL) Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 21, 2025
- Primary completion
- Oct 31, 2028
- Completion
- Jan 31, 2029
- Last update posted
- Apr 15, 2026
2025 – 2029
United States locations
- U.S. sites
- 54
- U.S. states
- 25
- U.S. cities
- 52
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Research Network Arizona | Scottsdale | Arizona | 85255 | Recruiting |
| Barnet Dulaney Perkins Eye Center | Sun City | Arizona | 85351 | Recruiting |
| Retina Associates | Tucson | Arizona | 85704 | Recruiting |
| Retinal Diagnostic Center | Campbell | California | 95008 | Recruiting |
| Retina Consultants of Orange County | Fullerton | California | 92835 | Recruiting |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | Recruiting |
| Retinal Consultants Medical Group Inc. | Sacramento | California | 95825 | Recruiting |
| Retinal Consultants Medical Group | Sacramento | California | 95841 | Recruiting |
| West Coast Retina Medical Group | San Francisco | California | 94109 | Recruiting |
| Bay Area Retina Associates | Walnut Creek | California | 94598 | Recruiting |
| Retina Consultants of Southern Colorado P.C. | Colorado Springs | Colorado | 80909 | Recruiting |
| Southwest Retina Consultants | Durango | Colorado | 81303 | Recruiting |
| ClearVista Clinical Research | Hudson | Florida | 34667 | Recruiting |
| Florida Retina Institute | Orlando | Florida | 32806 | Recruiting |
| Retina Specialty Institute | Pensacola | Florida | 32503 | Recruiting |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | Recruiting |
| East Florida Eye Institute | Stuart | Florida | 34994 | Recruiting |
| Retina Vitreous Associates of Florida | Tampa | Florida | 33617 | Recruiting |
| Thomas Eye Group | Sandy Springs | Georgia | 30328 | Recruiting |
| Retina Associates, Ltd. | Elmhurst | Illinois | 60126 | Recruiting |
| University Retina and Macula Associates, PC | Oak Forest | Illinois | 60452 | Recruiting |
| Illinois Retina Associates | Oak Park | Illinois | 60304 | Recruiting |
| Springfield Clinic | Springfield | Illinois | 62703 | Recruiting |
| Retina Partners Midwest, PC | Carmel | Indiana | 46032 | Recruiting |
| The Retina Care Center | Baltimore | Maryland | 21209 | Recruiting |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | Recruiting |
| Mid Atlantic Retina Specialist | Hagerstown | Maryland | 21740 | Recruiting |
| New England Retina Consultants | Springfield | Massachusetts | 01107 | Recruiting |
| Foundation for Vision Research | Grand Rapids | Michigan | 49546 | Recruiting |
| Sierra Eye Associates | Reno | Nevada | 89502 | Recruiting |
| Envision Ocular, LLC | Bloomfield | New Jersey | 07003 | Recruiting |
| Retina Vitreous Surgeons of CNY PC | Liverpool | New York | 13088 | Recruiting |
| New York Presbyterian Hospital - Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| Vitreoretinal Consultants of NY | Westbury | New York | 11590 | Recruiting |
| North Carolina Retina Associates | Cary | North Carolina | 27511 | Recruiting |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | Recruiting |
| Cincinnati Eye Institute | Cincinnati | Ohio | 45242 | Recruiting |
| Verum Research, LLC | Eugene | Oregon | 947401 | Recruiting |
| EyeHealth Northwest | Portland | Oregon | 97233 | Recruiting |
| Erie Retina Research | Erie | Pennsylvania | 16505 | Recruiting |
| Charleston Neuroscience Institute, LLC | Bluffton | South Carolina | 29910 | Recruiting |
| Carolina Eyecare | Mt. Pleasant | South Carolina | 29464 | Recruiting |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | Recruiting |
| Black Hills Regional Eye Institute | Rapid City | South Dakota | 57701 | Recruiting |
| Tennessee Retina, PC | Nashville | Tennessee | 37203 | Recruiting |
| Southwest Retina Specialist - Panhandle Eye group, LLP | Amarillo | Texas | 79106 | Recruiting |
| Austin Clinical Research | Austin | Texas | 78750 | Recruiting |
| Texas Retina Associate | Dallas | Texas | 75231 | Recruiting |
| Tyler Retina Consultants | Tyler | Texas | 75703 | Recruiting |
| Strategic Clinical Research | Willow Park | Texas | 76087 | Recruiting |
| Rocky Mountain Retina Consultants | Salt Lake City | Utah | 84107 | Recruiting |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | Recruiting |
| Pacific Northwest Retina | Silverdale | Washington | 98383 | Recruiting |
| Eye Clinic of Wisconsin | Wausau | Wisconsin | 54403 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 40 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07064759, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 15, 2026 · Synced May 20, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07064759 live on ClinicalTrials.gov.