Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Public ClinicalTrials.gov record NCT07069738. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study will compare two different methods to pace the heart to treat heart failure including: 1. The current standard method of implanting a pacing lead in a vein on the surface of the left lower chamber of the heart (left ventricle) to deliver heart failure therapy. This method is called Cardiac Resynchronization Therapy (CRT). 2. The other method is using a lead implanted in the Left Bundle Branch Area (LBBA) of your heart. This method is called Left Bundle Branch Area Pacing or LBBAP. This lead is approved by the Food and Drug Administration (FDA) to be implanted in this area of the heart, but not to provide heart failure treatment.
Study identification
- NCT ID
- NCT07069738
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 850 participants
Conditions and interventions
Conditions
Interventions
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 21, 2025
- Primary completion
- Oct 31, 2029
- Completion
- Oct 31, 2029
- Last update posted
- Sep 3, 2026
2025 – 2029
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research, LLC | Huntsville | Alabama | 35801 | Recruiting |
| Mobile Infirmary Medical Center | Mobile | Alabama | 36608 | Recruiting |
| Mayo Clinic Phoenix | Phoenix | Arizona | 85054 | Recruiting |
| Arrhythmia Research Group | Jonesboro | Arkansas | 72401 | Recruiting |
| Scripps Memorial Hospital | La Jolla | California | 92037 | Recruiting |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Alta Bates Summit Medical Center | Oakland | California | 94609 | Recruiting |
| Pacific Heart Institute | Santa Monica | California | 90404 | Recruiting |
| Torrance Medical Center | Torrance | California | 90505 | Recruiting |
| Cardiology Associates Medical Group, Inc. | Ventura | California | 93003 | Recruiting |
| Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | Recruiting |
| Sarasota Memorial Hospital | Sarasota | Florida | 34239 | Recruiting |
| AdventHealth Tampa | Tampa | Florida | 33613 | Recruiting |
| Piedmont Hospital | Atlanta | Georgia | 30309 | Recruiting |
| Emory University Hospital | Atlanta | Georgia | 30322 | Recruiting |
| University of Chicago | Hinsdale | Illinois | 60521 | Recruiting |
| Midwest Cardiovascular Institute | Naperville | Illinois | 60540 | Recruiting |
| Community Heart and Vascular Hospital | Indianapolis | Indiana | 46250 | Recruiting |
| University of Iowa Hospitals and Clinics | Iowa City | Iowa | 52242 | Recruiting |
| Baptist Hospital East Louisville | Louisville | Kentucky | 40207 | Recruiting |
| Southcoast Physicians Group | Fall River | Massachusetts | 02720 | Recruiting |
| University of Michigan Hospitals | Ann Arbor | Michigan | 48109 | Recruiting |
| Corewell Health | Grand Rapids | Michigan | 49525 | Recruiting |
| St. Mary's Duluth Clinic Regional Heart Center | Duluth | Minnesota | 55805 | Recruiting |
| Centracare Heart and Vascular Center | Saint Cloud | Minnesota | 56303 | Recruiting |
| Morristown Medical Center | Morristown | New Jersey | 07932 | Recruiting |
| Capital Cardiology Associates | Albany | New York | 12211 | Recruiting |
| New York Hospital Queens | Flushing | New York | 11355 | Recruiting |
| Weill Cornell Medical University | New York | New York | 10021 | Recruiting |
| Rochester General Hospital | New York | New York | 14621 | Recruiting |
| SUNY-Upstate Medical University | Syracuse | New York | 13057 | Recruiting |
| Sanger Heart and Vascular Institute | Charlotte | North Carolina | 28204 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| OhioHealth Research and Innovation Institute-Riverside Methodist Hospital | Columbus | Ohio | 43214 | Recruiting |
| Mount Carmel Health System | Columbus | Ohio | 43219 | Recruiting |
| Penn Presbyterian Medical Center | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Avera Heart Hospital of South Dakota | Sioux Falls | South Dakota | 57108 | Recruiting |
| St.Thomas Health | Nashville | Tennessee | 37205 | Recruiting |
| Heart Hospital Baylor Plano | Plano | Texas | 75093 | Recruiting |
| Christus Trinity Mother Frances Health System | Tyler | Texas | 75701 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07069738, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07069738 live on ClinicalTrials.gov.