A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Public ClinicalTrials.gov record NCT07081958. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center, Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Once-Daily RO7795081 Administered for 38 Weeks to Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tolerability, and safety of RO7795081 for chronic weight management in adult participants with obesity or overweight with at least one weight-related comorbidity, but without diabetes mellitus.
Study identification
- NCT ID
- NCT07081958
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 352 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 29, 2025 (Actual)
- Primary completion
- Apr 28, 2026 (Actual)
- Completion
- Jul 30, 2026 (Actual)
- Last update posted
- Oct 26, 2026
2025 – 2026
United States locations
- U.S. sites
- 36
- U.S. states
- 17
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Orange County Research Center | Lake Forest | California | 92630 | — |
| Prospective Research Innovations Inc. | Rancho Cucamonga | California | 91730 | — |
| Asclepes Research Centers | Sherman Oaks | California | 91403 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Chase Medical Research | Waterbury | Connecticut | 06708-3346 | — |
| Emerson Clinical Research Institute LLC | Washington D.C. | District of Columbia | 20009 | — |
| K2 Medical Research-Winter Garden | Clermont | Florida | 34711 | — |
| K2 Medical Research-Maitland | Maitland | Florida | 32751 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Accellacare of Duly Health and Care | Oak Lawn | Illinois | 60453 | — |
| Accellacare of McFarland | Ames | Iowa | 50010 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | — |
| Accellacare of Cary - Cary Medical Group | Cary | North Carolina | 27518 | — |
| Accellacare - Hickory | Hickory | North Carolina | 28601 | — |
| Accellacare of Raleigh | Raleigh | North Carolina | 27609 | — |
| Accellacare of Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Accellacare of Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare of Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Accellacare of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Accellacare Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Alliance for Multispecialty Research, LLC (AMR Norman) | Norman | Oklahoma | 73069 | — |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | 19114 | — |
| Internal Medicine and Pediatrics Associates of Bristol | Bristol | Tennessee | 37620 | — |
| Alliance for Multispecialty Research. LLC | Knoxville | Tennessee | 37909 | — |
| Accellacare of Knoxville | Knoxville | Tennessee | 37912 | — |
| Knoxville-Summit-Halls Family Practice | Knoxville | Tennessee | 37938 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78731 | — |
| Apex Mobile Clinical Research | Bellaire | Texas | 77401 | — |
| Velocity Clinical Research | Dallas | Texas | 75230 | — |
| Juno Research, LLC | Houston | Texas | 77040 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07081958, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 26, 2026 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07081958 live on ClinicalTrials.gov.