A Study Evaluating the Effect of Daily Oral RO7795081 in Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Public ClinicalTrials.gov record NCT07081958. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Multi-Center, Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Once-Daily RO7795081 Administered for 38 Weeks to Participants With Obesity or Overweight With at Least One Weight-Related Comorbidity
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This multicenter, randomized, double-blind, placebo-controlled, parallel-group, dose-range-finding, Phase II study aims to evaluate the efficacy, tolerability, and safety of RO7795081 for chronic weight management in adult participants with obesity or overweight with at least one weight-related comorbidity, but without diabetes mellitus.
Study identification
- NCT ID
- NCT07081958
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 352 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 28, 2025
- Primary completion
- Apr 27, 2026
- Completion
- Jul 29, 2026
- Last update posted
- Aug 20, 2026
2025 – 2026
United States locations
- U.S. sites
- 36
- U.S. states
- 17
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group | Anniston | Alabama | 36207 | — |
| Orange County Research Center | Lake Forest | California | 92630 | — |
| Prospective Research Innovations Inc. | Rancho Cucamonga | California | 91730 | — |
| Asclepes Research Centers | Sherman Oaks | California | 91403 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Chase Medical Research | Waterbury | Connecticut | 06708-3346 | — |
| Emerson Clinical Research Institute LLC | Washington D.C. | District of Columbia | 20009 | — |
| K2 Medical Research-Winter Garden | Clermont | Florida | 34711 | — |
| K2 Medical Research-Maitland | Maitland | Florida | 32751 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Accellacare of Duly Health and Care | Oak Lawn | Illinois | 60453 | — |
| McFarland Clinic under Accellacare | Ames | Iowa | 50010 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | — |
| Accellacare of Cary - Cary Medical Group | Cary | North Carolina | 27518 | — |
| Accellacare - Hickory | Hickory | North Carolina | 28601 | — |
| Accellacare of Raleigh | Raleigh | North Carolina | 27609 | — |
| Accellacare of Rocky Mount | Rocky Mount | North Carolina | 27804 | — |
| Accellacare of Salisbury | Salisbury | North Carolina | 28144 | — |
| Accellacare of Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Accellacare of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| Accellacare Research of Winston Salem | Winston-Salem | North Carolina | 27103 | — |
| Alliance for Multispecialty Research, LLC (AMR Norman) | Norman | Oklahoma | 73069 | — |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | 19114 | — |
| Internal Medicine and Pediatrics Associates of Bristol | Bristol | Tennessee | 37620 | — |
| Alliance for Multispecialty Research. LLC | Knoxville | Tennessee | 37909 | — |
| Accellacare of Knoxville | Knoxville | Tennessee | 37912 | — |
| Knoxville-Summit-Halls Family Practice | Knoxville | Tennessee | 37938 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78731 | — |
| Apex Mobile Clinical Research | Bellaire | Texas | 77401 | — |
| Velocity Clinical Research | Dallas | Texas | 75230 | — |
| Juno Research, LLC | Houston | Texas | 77040 | — |
| Consano Clinical Research | Shavano Park | Texas | 78231 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07081958, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 20, 2026 · Synced Sep 22, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07081958 live on ClinicalTrials.gov.