Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction
Public ClinicalTrials.gov record NCT07082816. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Prospective, Double-Masked, Randomized, Multi-Center, Active-Controlled, Parallel Group Comparison Study Assessing the Ocular Hypotensive Efficacy of Reformulated PG324 Ophthalmic Solution in Subjects With Elevated Intraocular Pressure
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is designed to see how safe and effective a new eye drop, called Reformulated PG324, is for lowering eye pressure in people with open-angle glaucoma (OAG) or ocular hypertension (OHT).
Study identification
- NCT ID
- NCT07082816
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 489 participants
Conditions and interventions
Conditions
Interventions
- Netarsudil 0.01%/latanoprost 0.005% ophthalmic solution Drug
- Netarsudil 0.02%/latanoprost 0.005% ophthalmic solution Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 2, 2025 (Actual)
- Primary completion
- Apr 6, 2026 (Actual)
- Completion
- Apr 6, 2026 (Actual)
- Last update posted
- Apr 21, 2026
2025 – 2026
United States locations
- U.S. sites
- 30
- U.S. states
- 16
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Trinity Research Group | Dothan | Alabama | 36301 | — |
| Eye Doctors of Arizona | Phoenix | Arizona | 85028 | — |
| Orange County Ophthalmology Medical Group | Garden Grove | California | 92843 | — |
| United Medical Research Institute | Inglewood | California | 90301 | — |
| Eye Research Foundation | Newport Beach | California | 92663 | — |
| North Bay Eye Associates | Petaluma | California | 94954 | — |
| Sacramento Eye Consultants | Sacramento | California | 95815 | — |
| Central Florida Eye Specialists | DeLand | Florida | 32720 | — |
| Glaucoma Specialists of South Florida | Delray Beach | Florida | 33484 | — |
| East Coast Institute for Research, LLC | Jacksonville | Florida | 32256 | — |
| Central Florida Eye Associates | Lakeland | Florida | 33805 | — |
| The Eye Institute of West Florida | Largo | Florida | 33770 | — |
| Lee Shettle Eye | Largo | Florida | 33773 | — |
| North Georgia Eye Associates | Gainesville | Georgia | 30501 | — |
| Coastal Research Associates | Roswell | Georgia | 30076 | — |
| Kannarr Eye Care LLC | Pittsburg | Kansas | 66762 | — |
| NorthEast Eye Research Associates, LLC | Westborough | Massachusetts | 01581 | — |
| Coldwater Vision Research | Coldwater | Mississippi | 38618 | — |
| Las Vegas Eye Institute | Henderson | Nevada | 89052 | — |
| Rochester Ophthalmological Group | Rochester | New York | 14618 | — |
| Albemarle Eye Center | Elizabeth City | North Carolina | 27909 | — |
| Oculus Research, Inc. | Garner | North Carolina | 27529 | — |
| CORE, Inc. | Shelby | North Carolina | 28150 | — |
| Midwest Eye Center | Cincinnati | Ohio | 45236 | — |
| University Hospitals Cleveland Medical Center | Cleveland | Ohio | 44106 | — |
| Scott & Christie and Associates, PC | Cranberry Township | Pennsylvania | 16066 | — |
| Southern College of Optometry | Memphis | Tennessee | 38104 | — |
| Total Eye Care, PA | Memphis | Tennessee | 38119 | — |
| The Eye Institute of Utah | Salt Lake City | Utah | 84107 | — |
| Piedmont Eye Center | Lynchburg | Virginia | 24502 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07082816, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 21, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07082816 live on ClinicalTrials.gov.