Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema
Public ClinicalTrials.gov record NCT07095361. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema (ONLY ONCE)
Study identification
- NCT ID
- NCT07095361
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Enrollment
- 270 participants
Conditions and interventions
Conditions
Interventions
- DNA degradation once daily Drug
- DNA degradation twice daily Drug
- Fibrinolytic once daily Drug
- Fibrinolytic twice daily Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 10, 2025
- Primary completion
- Sep 29, 2028
- Completion
- Sep 29, 2028
- Last update posted
- May 18, 2026
2025 – 2028
United States locations
- U.S. sites
- 6
- U.S. states
- 5
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Yale New Haven Hospital | New Haven | Connecticut | 06510 | Recruiting |
| Northwestern University | Chicago | Illinois | 60611 | Recruiting |
| Rush University Medical Center | Chicago | Illinois | 60612 | Recruiting |
| Henry Ford Hospital | Detroit | Michigan | 48202 | Recruiting |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03766 | Recruiting |
| UNC Chapel Hill | Chapel Hill | North Carolina | 27514 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07095361, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 18, 2026 · Synced May 20, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07095361 live on ClinicalTrials.gov.