Dabrafenib and Trametinib for BRAF V600 Mutant Low-Grade Gliomas
Public ClinicalTrials.gov record NCT07110246. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2 De-escalation Study of Dabrafenib and Trametinib for Patients With BRAF V600 Mutant Low-Grade Gliomas
Study identification
- NCT ID
- NCT07110246
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- University of California, San Francisco
- Other
- Enrollment
- 96 participants
Conditions and interventions
Interventions
- Dabrafenib Drug
- Magnetic Resonance Imaging (MRI) Procedure
- Optional Lumbar puncture Procedure
- Specimen Collection Procedure
- Trametinib Drug
Drug · Procedure
Eligibility (public fields only)
- Age range
- 12 Months to 25 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2025
- Primary completion
- Mar 30, 2032
- Completion
- Mar 30, 2032
- Last update posted
- Apr 29, 2026
2025 – 2032
United States locations
- U.S. sites
- 5
- U.S. states
- 5
- U.S. cities
- 5
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | Recruiting |
| University of California, San Francisco | San Francisco | California | 94143 | Recruiting |
| John Hopkins Medical Center | Baltimore | Maryland | 21287 | Recruiting |
| St. Louis Children's Hospital Washington University in St. Louis | St Louis | Missouri | 63110 | Recruiting |
| St. Jude Children's Research Hospital | Memphis | Tennessee | 38105 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07110246, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 29, 2026 · Synced May 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07110246 live on ClinicalTrials.gov.