A Study to Compare Different Doses of RO7795081 With a Placebo or Semaglutide in People With Type 2 Diabetes
Public ClinicalTrials.gov record NCT07112872. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-Blind, Placebo- and Open-Label Active Comparator- Controlled, Parallel-Group, Multi-Center Phase II Study to Evaluate the Efficacy, Safety, and Tolerability of Once-Daily RO7795081 Administered for 30 Weeks to Participants With Type 2 Diabetes Mellitus
Study identification
- NCT ID
- NCT07112872
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Hoffmann-La Roche
- Industry
- Enrollment
- 240 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- RO7795081 Drug
- Semaglutide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 18, 2025
- Primary completion
- Nov 26, 2026
- Completion
- Nov 26, 2026
- Last update posted
- Apr 7, 2026
2025 – 2026
United States locations
- U.S. sites
- 24
- U.S. states
- 16
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Liver Health - Tucson | Tucson | Arizona | 85712 | — |
| Orange County Research Center | Lake Forest | California | 92630 | — |
| Prospective Research Innovations Inc. | Rancho Cucamonga | California | 91730 | — |
| Encompass Clinical Research | Spring Valley | California | 91978 | — |
| Chase Medical Research | Waterbury | Connecticut | 06708-3346 | — |
| Emerson Clinical Research Institute | Washington D.C. | District of Columbia | 20009 | — |
| K2 Medical Research South Orlando, LLC | Clermont | Florida | 34711 | — |
| Center for Diabetes, Obesity and Metabolism Inc | Pembroke Pines | Florida | 33024 | — |
| Rophe Adult and Pediatric Medicine/SKYCRNG | Union City | Georgia | 30291 | — |
| Accellacare of Duly Health and Care | Oak Lawn | Illinois | 60453 | — |
| Mercury Street Medical Group, PLLC | Butte | Montana | 59701 | — |
| Neurobehavioral Research, Inc. | Cedarhurst | New York | 11516 | — |
| Accellacare of Piedmont Healthcare | Statesville | North Carolina | 28625 | — |
| Accellacare of Wilmington, LLC | Wilmington | North Carolina | 28401 | — |
| NexGen Research | Lima | Ohio | 45801 | — |
| Tristar Clinical Investigations | Philadelphia | Pennsylvania | 19114 | — |
| Alliance for Multispecialty Research. LLC | Knoxville | Tennessee | 37909 | — |
| Clinical Research Associates | Nashville | Tennessee | 37203 | — |
| Texas Diabetes & Endocrinology, P.A. | Austin | Texas | 78731 | — |
| Apex Mobile Clinical Research | Bellaire | Texas | 77401 | — |
| Velocity Clinical Research | Dallas | Texas | 75230 | — |
| Velocity Clinical Research (Impact Research Institute) | Waco | Texas | 76710 | — |
| Chrysalis Clinical Research | St. George | Utah | 84790 | — |
| Manassas Clinical Research Center | Manassas | Virginia | 20110 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07112872, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 7, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07112872 live on ClinicalTrials.gov.