ClinicalTrials.gov record
Recruiting Phase 1 Interventional

A Study of LY4257496 in Participants With Cancer (OMNIRAY)

ClinicalTrials.gov ID: NCT07114601

Public ClinicalTrials.gov record NCT07114601. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 6, 2026, 8:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1a/b Multicenter, Open-Label Trial to Evaluate Safety, Tolerability, and Dosimetry of LY4257496, a GRPR-Targeted Radioligand Therapy, in Adults With GRPR-Positive Advanced Solid Tumors (OMNIRAY)

Study identification

NCT ID
NCT07114601
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
421 participants

Conditions and interventions

Interventions

  • LY4257496 Drug
  • LY4257529 Diagnostic Test
  • Standard of Care Anticancer Therapies Drug

Drug · Diagnostic Test

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 5, 2025
Primary completion
Mar 31, 2030
Completion
Mar 31, 2035
Last update posted
Apr 16, 2026

2025 – 2035

United States locations

U.S. sites
15
U.S. states
8
U.S. cities
13
Facility City State ZIP Site status
City of Hope Duarte California 91010 Not yet recruiting
University of California, Los Angeles (UCLA) Santa Monica California 90404 Recruiting
Stanford University Medical Center Stanford California 94305 Recruiting
Biogenix Molecular, LLC Miami Florida 33165 Recruiting
Moffitt Tampa Florida 33612 Not yet recruiting
Emory University School of Medicine - Winship Cancer Institute Atlanta Georgia 30322 Not yet recruiting
Massachusetts General Hospital Boston Massachusetts 02114 Not yet recruiting
Dana-Farber Cancer Institute Boston Massachusetts 02215 Not yet recruiting
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 Recruiting
BAMF Health Inc. Grand Rapids Michigan 49503 Recruiting
Washington University St Louis Missouri 63110 Recruiting
New York University (NYU) Langone Medical Center New York New York 10016 Not yet recruiting
David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center New York New York 10065 Recruiting
Texas Oncology - DFW (Sammons CC) Dallas Texas 75246 Not yet recruiting
MD Anderson Cancer Center Houston Texas 77030 Not yet recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 13 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07114601, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2026 · Synced May 6, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT07114601 live on ClinicalTrials.gov.

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