A Study to Evaluate Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Public ClinicalTrials.gov record NCT07124078. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Open-Label Study of Axatilimab Versus Best Available Therapy in Pediatric Participants With Chronic Graft-Versus-Host Disease After at Least 2 Prior Lines of Systemic Therapy (AGAVE-256)
Study identification
- NCT ID
- NCT07124078
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Incyte Corporation
- Industry
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Interventions
- Best available Treatment (BAT) Drug
- INCA034176 Drug
Drug
Eligibility (public fields only)
- Age range
- 2 Years to 17 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 30, 2026
- Primary completion
- Jan 30, 2029
- Completion
- Jul 30, 2029
- Last update posted
- May 6, 2026
2026 – 2029
United States locations
- U.S. sites
- 11
- U.S. states
- 8
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| City of Hope Medical Center | Duarte | California | 91010 | Recruiting |
| Children'S Hospital Los Angeles Specialt | Los Angeles | California | 90027 | Not yet recruiting |
| Lucile Packard Child Hospital End | Palo Alto | California | 94304 | Not yet recruiting |
| Childrens National Medical Center | Washington D.C. | District of Columbia | 20010 | Not yet recruiting |
| Adventhealth Pediatric Cellular Therapy and Blood and Marrow Transplant | Orlando | Florida | 32804 | Not yet recruiting |
| Childrens Healthcare of Atlanta | Atlanta | Georgia | 30329 | Not yet recruiting |
| Memorial Sloan Kettering Cancer Center | New York | New York | 10065 | Recruiting |
| Levine Cancer Institute | Charlotte | North Carolina | 28203 | Recruiting |
| Duke Cancer Center | Durham | North Carolina | 27710 | Not yet recruiting |
| Childrens Hospital of Pittsburgh | Pittsburgh | Pennsylvania | 15224 | Not yet recruiting |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 29 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07124078, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 6, 2026 · Synced May 8, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07124078 live on ClinicalTrials.gov.