A Study of PHN-012 in Patients With Advanced Solid Tumors
Public ClinicalTrials.gov record NCT07127874. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
First-in-Human, Phase 1 Study of PHN-012, an Antibody Drug Conjugate, in Patients With Advanced Solid Tumors
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This first-in-human study will evaluate safety, tolerability, anti-tumor activity, immunogenicity, pharmacokinetics and pharmacodynamics of PHN-012, a novel antibody-drug conjugate (ADC), in patients with advanced solid tumors.
Study identification
- NCT ID
- NCT07127874
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 165 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 23, 2025 (Actual)
- Primary completion
- Sep 2027 (Estimated)
- Completion
- May 2028 (Estimated)
- Last update posted
- Sep 29, 2026
2025 – 2028
United States locations
- U.S. sites
- 11
- U.S. states
- 9
- U.S. cities
- 11
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| PHN-012-001 Site | Los Angeles | California | 90033 | Recruiting |
| PHN-012-001 Site | San Diego | California | 92037 | Recruiting |
| PHN-012-001 Site | Washington D.C. | District of Columbia | 20007 | Recruiting |
| PHN-012-001 Site | Boston | Massachusetts | 02114 | Recruiting |
| PHN-012-001 Site | St Louis | Missouri | 63108 | Recruiting |
| PHN-012-001 Site | Durham | North Carolina | 27710 | Recruiting |
| PHN-012-001 Site | Portland | Oregon | 97239 | Recruiting |
| PHN-012-001 Site | Nashville | Tennessee | 37203 | Recruiting |
| PHN-012-001 Site | Houston | Texas | 77030 | Recruiting |
| PHN-012-001 Site | San Antonio | Texas | 78229 | Recruiting |
| PHN-012-001 Site | Fairfax | Virginia | 22031 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 15 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07127874, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2026 · Synced Oct 3, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07127874 live on ClinicalTrials.gov.