OPI-NXYDLD-303 Safety and Efficacy of Phentolamine Ophthalmic Solution in Keratorefractive Surgery Participants With Decreased Mesopic Visual Acuity
Public ClinicalTrials.gov record NCT07140783. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-MASKED STUDY OF THE SAFETY AND EFFICACY OF POS (0.75% PHENTOLAMINE OPHTHALMIC SOLUTION) IN PARTICIPANTS WITH PREVIOUS KERATOREFRACTIVE SURGERY WITH DECREASED VISUAL ACUITY UNDER MESOPIC CONDITIONS
Study identification
- NCT ID
- NCT07140783
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Ocuphire Pharma, Inc.
- Industry
- Enrollment
- 200 participants
Conditions and interventions
Conditions
Interventions
- 0.75% Phentolamine Ophthalmic Solution Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 1, 2025
- Primary completion
- Feb 28, 2026
- Completion
- Feb 28, 2026
- Last update posted
- Sep 30, 2025
2025 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 10
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Eye Care | Chandler | Arizona | 85224 | Recruiting |
| Carrot Eye Center | Mesa | Arizona | 85202 | Recruiting |
| Eye Doctors of Arizona | Phoenix | Arizona | 85028 | Recruiting |
| MRB Eye Care Consultants | Scottsdale | Arizona | 85254 | Recruiting |
| Global Research Management | Glendale | California | 91204 | Recruiting |
| Gordon Schanzlin New Vision | La Jolla | California | 92037 | Recruiting |
| Eye Research Foundation | Newport Beach | California | 92663 | Recruiting |
| California Eye Specialists Medical Group | Pasadena | California | 91107 | Recruiting |
| NVISION Clinical Research | San Diego | California | 92117 | Recruiting |
| Scripps Poway Eyecare and Optometry | San Diego | California | 92130 | Recruiting |
| Wolsten and Goldberg Eye Assoc. | Torrance | California | 90505 | Recruiting |
| Glaucoma Specialist of South Florida | Delray Beach | Florida | 33484 | Recruiting |
| Segal Drug Trials | Delray Beach | Florida | 33484 | Recruiting |
| Wyse Eyecare | Northbrook | Illinois | 60062 | Recruiting |
| Virdi Eye Clinic | Rock Island | Illinois | 61201 | Recruiting |
| Durrie Vision | Overland Park | Kansas | 66210 | Recruiting |
| Kannarr Eye Care | Pittsburg | Kansas | 66762 | Recruiting |
| Eye Health Vision Center | South Dartmouth | Massachusetts | 02747 | Recruiting |
| Northeast Eye Research Associates | Woburn | Massachusetts | 01801 | Recruiting |
| Oculus Research | Garner | North Carolina | 27529 | Recruiting |
| West Bay Eye Assoc. | Warwick | Rhode Island | 02888 | Recruiting |
| Zillan Clinical Research | Houston | Texas | 77082 | Recruiting |
| Hoopes Vision | Draper | Utah | 84020 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07140783, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 30, 2025 · Synced May 19, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07140783 live on ClinicalTrials.gov.