A Study of Pasritamig Versus Placebo in Late Line Metastatic Castration-resistant Prostate Cancer (mCRPC)
Public ClinicalTrials.gov record NCT07164443. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-blind, Placebo-controlled Study of Pasritamig (JNJ-78278343), a T Cell Redirecting Agent Targeting Human Kallikrein 2, + Best Supportive Care Versus Best Supportive Care for Metastatic Castration-resistant Prostate Cancer
Study identification
- NCT ID
- NCT07164443
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Janssen Research & Development, LLC
- Industry
- Enrollment
- 663 participants
Conditions and interventions
Interventions
- Best Supportive Care (BSC) Drug
- Pasritamig Biological
- Placebo Other
Drug · Biological · Other
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Male
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 1, 2025
- Primary completion
- May 29, 2028
- Completion
- May 29, 2028
- Last update posted
- Apr 12, 2026
2025 – 2028
United States locations
- U.S. sites
- 47
- U.S. states
- 21
- U.S. cities
- 41
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of California at San Diego | La Jolla | California | 92093 | Recruiting |
| Ronald Reagan UCLA Medical Center | Los Angeles | California | 90095 | Recruiting |
| Rocky Mountain Cancer Centers | Aurora | Colorado | 80012 | Recruiting |
| University of Colorado Cancer Center | Aurora | Colorado | 80045 | Recruiting |
| Colorado Clinical Research | Lakewood | Colorado | 80228 | Recruiting |
| Hartford Hospital | Hartford | Connecticut | 06102 | Recruiting |
| Johns Hopkins Office of Capital Region Research - Sibley Memorial Hospital | Washington D.C. | District of Columbia | 20016 | Recruiting |
| Bay Pines VA Healthcare System | Bay Pines | Florida | 33744 | Recruiting |
| Florida Cancer Specialists & Research Institute | Fort Myers | Florida | 33901 | Recruiting |
| Moffitt Cancer Center | Tampa | Florida | 33612 | Recruiting |
| East Jefferson General Hospital | Metairie | Louisiana | 70006 | Recruiting |
| Johns Hopkins University | Baltimore | Maryland | 21287 | Recruiting |
| Dana Farber Cancer Institute | Boston | Massachusetts | 02115 | Recruiting |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | Recruiting |
| Henry Ford Cancer Detroit | Detroit | Michigan | 48202 | Recruiting |
| University Of Minnesota Medical Center | Minneapolis | Minnesota | 55455 | Recruiting |
| XCancer Omaha / Urology Cancer Center | Omaha | Nebraska | 68130 | Recruiting |
| NYU Langone Hospitals | Brooklyn | New York | 11220 | Recruiting |
| NYU Langone Hospital Long Island | Mineola | New York | 11501 | Recruiting |
| NYU Langone Health Laura and Isaac Perlmutter Cancer Center | New York | New York | 10016 | Recruiting |
| Columbia University Medical Center | New York | New York | 10032 | Recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45219 | Recruiting |
| University Hospital of Cleveland | Cleveland | Ohio | 44106 | Recruiting |
| Compass Oncology | Portland | Oregon | 97227 | Recruiting |
| Oregon Urology Institute | Springfield | Oregon | 97477 | Recruiting |
| MidLantic Urology | Bala-Cynwyd | Pennsylvania | 19004 | Recruiting |
| Keystone Urology Specialists | Lancaster | Pennsylvania | 17601 | Recruiting |
| Penn Medicine Abramson Cancer Center | Philadelphia | Pennsylvania | 19104 | Recruiting |
| UPMC Cancer Centers | Pittsburgh | Pennsylvania | 15232 | Recruiting |
| Ralph H Johnson Veterans Hospital | Charleston | South Carolina | 29401 | Recruiting |
| Gibbs Cancer Center and Research Institute Pelham | Greer | South Carolina | 29650 | Recruiting |
| Carolina Urologic Research Center | Myrtle Beach | South Carolina | 29572 | Recruiting |
| Gibbs Cancer Center | Spartanburg | South Carolina | 29303 | Recruiting |
| Tennessee Oncology - Chattanooga | Chattanooga | Tennessee | 37404 | Recruiting |
| Tennessee Oncology Nashville | Nashville | Tennessee | 37203 | Recruiting |
| Urology Clinics of North Texas | Dallas | Texas | 75231 | Recruiting |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | Recruiting |
| MD Anderson Cancer Center | Houston | Texas | 77030 | Recruiting |
| Michael E DeBakey VA Medical Center | Houston | Texas | 77030 | Recruiting |
| Texas Oncology West Texas | Wichita Falls | Texas | 76310 | Recruiting |
| Utah Cancer Specialists | Salt Lake City | Utah | 84106 | Recruiting |
| Virginia Cancer Specialists | Fairfax | Virginia | 22031 | Recruiting |
| Virginia Oncology Associates | Norfolk | Virginia | 23502 | Recruiting |
| Blue Ridge Cancer Care | Roanoke | Virginia | 24014 | Recruiting |
| VA Puget Sound Healthcare System | Seattle | Washington | 98108 | Recruiting |
| Fred Hutchinson Cancer Research Center | Seattle | Washington | 98109 | Recruiting |
| University of Washington | Seattle | Washington | 98195 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 116 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07164443, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 12, 2026 · Synced Apr 23, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07164443 live on ClinicalTrials.gov.