Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Public ClinicalTrials.gov record NCT07166094. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Open-label Study of Rinatabart Sesutecan (Rina-S) Versus Treatment of Investigator's Choice (IC) in Patients With Endometrial Cancer After Platinum-Based Chemotherapy and PD(L)-1 Therapy
Study identification
- NCT ID
- NCT07166094
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Genmab
- Industry
- Enrollment
- 660 participants
Conditions and interventions
Interventions
- IC Drug
- Rina-S Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- Female
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 27, 2025
- Primary completion
- Jul 31, 2029
- Completion
- Oct 31, 2029
- Last update posted
- May 5, 2026
2025 – 2029
United States locations
- U.S. sites
- 43
- U.S. states
- 11
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| MedStar Washington Hospital | Washington D.C. | District of Columbia | 20010 | Recruiting |
| SMH - Sarasota - Main Campus | Sarasota | Florida | 34239 | Recruiting |
| Women's Care - 9th Ave | St. Petersburg | Florida | 33713 | Recruiting |
| Emory Winship Cancer Inst. | Atlanta | Georgia | 30308 | Recruiting |
| Emory Winship Cancer Inst. | Atlanta | Georgia | 30322 | Recruiting |
| Emory Winship Cancer Inst./Emory Decatur Hospital | Decatur | Georgia | 30033 | Recruiting |
| Trials365, LLC | Shreveport | Louisiana | 71103 | Recruiting |
| Sinai Hospital | Baltimore | Maryland | 21215 | Recruiting |
| William Kahlert Reg. Can. Ctr | Westminster | Maryland | 21157 | Recruiting |
| USOR - Minnesota Oncology-Coon Rapids Clinic | Coon Rapids | Minnesota | 55433 | Recruiting |
| USOR - Minnesota Oncology/ Coon Rapids Clinic | Coon Rapids | Minnesota | 55433 | Recruiting |
| USOR - Minnesota Oncology - Edina Clinic | Edina | Minnesota | 55435 | Recruiting |
| USOR - Minnesota Oncology/Edina Clinic | Edina | Minnesota | 55435 | Recruiting |
| USOR - Minnesota Oncology/ Maple Grove Clinic | Maple Grove | Minnesota | 55369 | Recruiting |
| USOR - Minnesota Oncology-Maplewood Clinic | Maplewood | Minnesota | 55109 | Recruiting |
| USOR - Minnesota Oncology/ Maplewood Clinic | Maplewood | Minnesota | 55109 | Recruiting |
| USOR - Minnesota Oncology/ Minneapolis Clinic | Minneapolis | Minnesota | 55404 | Recruiting |
| USOR - Minnesota Oncology | Minneapolis | Minnesota | 55404 | Recruiting |
| USOR - Minnesota Oncology/ Woodbury Clinic | Woodbury | Minnesota | 55125 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45219 | Recruiting |
| Willamette Valley Cancer Institute and Research Center - Eugene | Eugene | Oregon | 97401 | Recruiting |
| NW Cancer Specs. P.C. | Happy Valley | Oregon | 97015 | Recruiting |
| USOR - NW Cancer Specs P.C. | Portland | Oregon | 97227 | Recruiting |
| USOR - NW Cancer Specs. P.C. | Tigard | Oregon | 97223 | Recruiting |
| TX Onc - Arlington North | Arlington | Texas | 76012 | Recruiting |
| USOR - Texas Oncology | Austin | Texas | 78731 | Recruiting |
| USOR - Texas Oncology | Austin | Texas | 78745 | Recruiting |
| USOR - Texas Oncology- Austin North | Austin | Texas | 78758 | Recruiting |
| TX Onc - Bedford | Bedford | Texas | 76022 | Recruiting |
| TX Onc - Methodist Dallas | Dallas | Texas | 75203 | Recruiting |
| TX Onc - Presbyterian Dallas | Dallas | Texas | 75231 | Recruiting |
| TX Onc - Methodist Charlton | Dallas | Texas | 75237 | Recruiting |
| TX Onc - Sammons | Dallas | Texas | 75246 | Recruiting |
| USOR - Texas Oncology - Dallas Fort Worth (DFW) | Fort Worth | Texas | 76104 | Recruiting |
| USOR - Texas Oncology | Harlingen | Texas | 78550 | Recruiting |
| USOR - Texas Oncology | McAllen | Texas | 78503 | Recruiting |
| USOR - TX Oncology - SA NE | San Antonio | Texas | 78217 | Recruiting |
| NEXT San Antonio | San Antonio | Texas | 78240 | Recruiting |
| USOR - Texas Oncology- Horizon Circle | Waco | Texas | 76712 | Recruiting |
| USOR - Texas Oncology- Waco | Waco | Texas | 76712 | Recruiting |
| USOR - Texas Oncology | Weslaco | Texas | 78596 | Recruiting |
| USOR - NW Cancer Specs P.C. | Vancouver | Washington | 98684 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 31 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07166094, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted May 5, 2026 · Synced May 6, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT07166094 live on ClinicalTrials.gov.