A Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease
Public ClinicalTrials.gov record NCT07169578. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (MCI to Mild Dementia Due to AD)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).
Study identification
- NCT ID
- NCT07169578
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,101 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 17, 2025 (Actual)
- Primary completion
- Feb 16, 2028 (Estimated)
- Completion
- Feb 16, 2028 (Estimated)
- Last update posted
- Sep 25, 2026
2025 – 2028
United States locations
- U.S. sites
- 35
- U.S. states
- 18
- U.S. cities
- 34
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35233 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Irvine Center for Clinical Research | Irvine | California | 92614 | — |
| Inglewood Clinicals | Los Angeles | California | 90056 | — |
| UCSF - Memory and Aging Center | San Francisco | California | 94158 | — |
| Syrentis Clinical Research | Santa Ana | California | 92705 | — |
| K2 Medical Research - The Villages | Lady Lake | Florida | 32159 | — |
| K2 Medical Research, LLC | Maitland | Florida | 32751 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Axiom Brain Health LLC | Tampa | Florida | 33609 | — |
| Charter Research - Lady Lake/The Villages | The Villages | Florida | 32162 | — |
| Alzheimer?s Research and Treatment Center | Wellington | Florida | 33414 | — |
| Conquest Research, LLC | Winter Park | Florida | 32789 | — |
| Alzheimer's Research and Treatment Center - Columbus | Columbus | Georgia | 31904 | — |
| Accel Research Sites-NeuroStudies | Decatur | Georgia | 30030 | — |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | 96817 | — |
| RE:Cognition (Chicago) | Chicago | Illinois | 60611 | — |
| Tandem Clinical Research, LLC | Marrero | Louisiana | 70072 | — |
| Brigham and Womens Hospital | Boston | Massachusetts | 02115 | — |
| Boston Center for Memory | Newton | Massachusetts | 02459 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| The Cognitive and Research Center of New Jersey | Ridgewood | New Jersey | 07450 | — |
| Basil Clinical | Laurelton | New York | 11413-2016 | — |
| Weill Cornell Medical College | New York | New York | 10021 | — |
| Adams Clinical Harlem | New York | New York | 10029 | — |
| Adams Clinical Bronx | The Bronx | New York | 10461 | — |
| Triad Clinical Trials | Greensboro | North Carolina | 27410 | — |
| Ohio State University | Columbus | Ohio | 43221 | — |
| Butler Hospital | Providence | Rhode Island | 02906 | — |
| Genesis Neuroscience Clinic | Knoxville | Tennessee | 37909 | — |
| K2 Medical Research - Nashville | Nashville | Tennessee | 37204 | — |
| Kerwin Research Center, LLC | Dallas | Texas | 75231 | — |
| South Texas Research Institute - Edinburg | Edinburg | Texas | 78539 | — |
| Re:Cognition Health - Houston | Houston | Texas | 77030 | — |
| National Clinical Research Inc.-Richmond | Richmond | Virginia | 23294 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 107 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT07169578, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT07169578 live on ClinicalTrials.gov.