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Active, not recruiting Phase 3 Interventional

A Clinical Trial of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease

ClinicalTrials.gov ID: NCT07170150

Public ClinicalTrials.gov record NCT07170150. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 19, 2026, 1:49 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase III, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Efficacy and Safety Study of Trontinemab in Participants With Early Symptomatic Alzheimer's Disease (MCI to Mild Dementia Due to AD)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the efficacy and safety of trontinemab in participants with early symptomatic Alzheimer's disease (AD) (mild cognitive impairment \[MCI\] to mild dementia due to AD).

Study identification

NCT ID
NCT07170150
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 3
Lead sponsor
Hoffmann-La Roche
Industry
Enrollment
1,060 participants

Conditions and interventions

Interventions

Drug · Other

Eligibility (public fields only)

Age range
50 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 12, 2025 (Actual)
Primary completion
Feb 16, 2028 (Estimated)
Completion
Feb 16, 2028 (Estimated)
Last update posted
Sep 25, 2026

2025 – 2028

United States locations

U.S. sites
33
U.S. states
17
U.S. cities
32
Facility City State ZIP Site status
Banner Alzheimer?s Institute Phoenix Arizona 85006 —
Sun Valley Research Center, Inc. Imperial California 92251 —
Healthy Brain Clinic Long Beach California 90804 —
Oakland Clinical Oakland California 94609 —
Riverside Clinical Riverside California 92506 —
Cenexel California Neuroscience Research, LLC Sherman Oaks California 91403 —
Yale University New Haven Connecticut 06510 —
JEM Research LLC Atlantis Florida 33462 —
K2 Medical Research-Winter Garden Clermont Florida 34711 —
Visionary Investigators Network- Neurology Aventura Miami Florida 33133 —
Charter Research - Winter Park/Orlando Orlando Florida 32803 —
Conquest Research - Lake Nona Orlando Florida 32832 —
Alzheimer's Research and Treatment Center Stuart Florida 34996 —
CenExel iResearch, LLC Decatur Georgia 30030 —
Center for Advanced Research & Education Gainesville Georgia 30501 —
Great Lakes Clinical Trials Chicago d/b/a Flourish Research Andersonville Chicago Illinois 60640 —
Adams Clinical Boston Boston Massachusetts 02116 —
Adams Clinical Watertown Watertown Massachusetts 02472 —
Quest Research Institute Farmington Hills Michigan 48334 —
University of Nebraska Medical Center Omaha Nebraska 68198-8440 —
The Cognitive and Research Center of New Jersey Springfield New Jersey 07081 —
IMA Clinical Research - Albuquerque Albuquerque New Mexico 87109 —
AD-CARE, University of Rochester Medical Center Rochester New York 14620 —
Summit Research Network Inc. Portland Oregon 97210 —
Flourish Research ? Philadelphia Plymouth Meeting Pennsylvania 19462 —
Palmetto Clinical Trials Summerville South Carolina 29485 —
Gadolin Research, LLC Beaumont Texas 77702 —
Kerwin Medical Center Dallas Texas 75216 —
Re:Cognition Health - Fort Worth Fort Worth Texas 76104 —
Mt.Olympus Medical Research Katy Texas 77450 —
El Faro Health and Therapeutics Rio Grande City Texas 78582 —
Sana Research, LLC Arlington Virginia 22205 —
Re:Cognition Health Fairfax Virginia 22031 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 114 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT07170150, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 25, 2026 · Synced Oct 19, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT07170150 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →